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Hematopoietic Stem Cell Function in a Murine Model of Sickle Cell Disease

Previous studies have shown that the sickle environment is highly enriched for reactive oxygen species (ROS). We examined the oxidative effects of sickle cell disease on hematopoietic stem cell function in a sickle mouse model. In vitro colony-forming assays showed a significant decrease in progenit...

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Detalles Bibliográficos
Autores principales:	Javazon, Elisabeth H., Radhi, Mohamed, Gangadharan, Bagirath, Perry, Jennifer, Archer, David R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372279/ https://www.ncbi.nlm.nih.gov/pubmed/22701784 http://dx.doi.org/10.1155/2012/387385

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