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Transplacental Chikungunya Virus Antibody Kinetics, Thailand

Antibodies to chikungunya virus were detected by hemagglutination-inhibition assay in 33.6% of 2,000 infants' cord sera at delivery. Follow-up of 24 seropositive infants showed that the half-life of antibody persistence was 35.5 days. Chikungunya virus infection is common in Thailand, and routi...

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Detalles Bibliográficos
Autores principales: Watanaveeradej, Veerachai, Endy, Timothy P., Simasathien, Sriluck, Kerdpanich, Angkool, Polprasert, Napuschon, Aree, Chanchai, Vaughn, David W., Nisalak, Ananda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372326/
https://www.ncbi.nlm.nih.gov/pubmed/17283634
http://dx.doi.org/10.3201/eid1211.050560
Descripción
Sumario:Antibodies to chikungunya virus were detected by hemagglutination-inhibition assay in 33.6% of 2,000 infants' cord sera at delivery. Follow-up of 24 seropositive infants showed that the half-life of antibody persistence was 35.5 days. Chikungunya virus infection is common in Thailand, and routine use of diagnostic assays is needed.