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Fibril-Forming Motifs Are Essential and Sufficient for the Fibrillization of Human Tau
BACKGROUND: The misfolding of amyloidogenic proteins including human Tau protein, human prion protein, and human α-synuclein is involved in neurodegenerative diseases such as Alzheimer disease, prion disease, and Parkinson disease. Although a lot of research on such amyloidogenic proteins has been d...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372541/ https://www.ncbi.nlm.nih.gov/pubmed/22701727 http://dx.doi.org/10.1371/journal.pone.0038903 |