Targeted Therapy: A New Approach for the Treatment of Locally Advanced Oropharyngeal Cancer

Presented herein is a clinical study comprising 48 patients (42 men and 6 women) of working age (40–70 years), all of whom are suffering from locally advanced oropharyngeal cancer. A modern approach is applied to treat these patients,i.e., neoadjuvant targeted therapy, taking into account the biolog...

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Detalles Bibliográficos
Autores principales: Velsher, L.Z., Kosmynin, A.A., Byakhov, M.Yu., Duditskaya, T.K., Reshetov, D.N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372996/
https://www.ncbi.nlm.nih.gov/pubmed/22708067
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author Velsher, L.Z.
Kosmynin, A.A.
Byakhov, M.Yu.
Duditskaya, T.K.
Reshetov, D.N.
author_facet Velsher, L.Z.
Kosmynin, A.A.
Byakhov, M.Yu.
Duditskaya, T.K.
Reshetov, D.N.
author_sort Velsher, L.Z.
collection PubMed
description Presented herein is a clinical study comprising 48 patients (42 men and 6 women) of working age (40–70 years), all of whom are suffering from locally advanced oropharyngeal cancer. A modern approach is applied to treat these patients,i.e., neoadjuvant targeted therapy, taking into account the biological profile of the tumor. The use of gefitinib causes an antitumor effect in 90.5% of cases as opposed to 56.5% when no drug is applied.
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spelling pubmed-33729962012-06-15 Targeted Therapy: A New Approach for the Treatment of Locally Advanced Oropharyngeal Cancer Velsher, L.Z. Kosmynin, A.A. Byakhov, M.Yu. Duditskaya, T.K. Reshetov, D.N. Acta Naturae Research Article Presented herein is a clinical study comprising 48 patients (42 men and 6 women) of working age (40–70 years), all of whom are suffering from locally advanced oropharyngeal cancer. A modern approach is applied to treat these patients,i.e., neoadjuvant targeted therapy, taking into account the biological profile of the tumor. The use of gefitinib causes an antitumor effect in 90.5% of cases as opposed to 56.5% when no drug is applied. A.I. Gordeyev 2012 /pmc/articles/PMC3372996/ /pubmed/22708067 Text en Copyright © 2012 Park-media Ltd. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Velsher, L.Z.
Kosmynin, A.A.
Byakhov, M.Yu.
Duditskaya, T.K.
Reshetov, D.N.
Targeted Therapy: A New Approach for the Treatment of Locally Advanced Oropharyngeal Cancer
title Targeted Therapy: A New Approach for the Treatment of Locally Advanced Oropharyngeal Cancer
title_full Targeted Therapy: A New Approach for the Treatment of Locally Advanced Oropharyngeal Cancer
title_fullStr Targeted Therapy: A New Approach for the Treatment of Locally Advanced Oropharyngeal Cancer
title_full_unstemmed Targeted Therapy: A New Approach for the Treatment of Locally Advanced Oropharyngeal Cancer
title_short Targeted Therapy: A New Approach for the Treatment of Locally Advanced Oropharyngeal Cancer
title_sort targeted therapy: a new approach for the treatment of locally advanced oropharyngeal cancer
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372996/
https://www.ncbi.nlm.nih.gov/pubmed/22708067
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