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Severe Community-acquired Pneumonia Due to Staphylococcus aureus, 2003–04 Influenza Season

During the 2003–04 influenza season, 17 cases of Staphylococcus aureus community-acquired pneumonia (CAP) were reported from 9 states; 15 (88%) were associated with methicillin-resistant S. aureus (MRSA). The median age of patients was 21 years; 5 (29%) had underlying diseases, and 4 (24%) had risk...

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Autores principales: Hageman, Jeffrey C., Uyeki, Timothy M., Francis, John S., Jernigan, Daniel B., Wheeler, J. Gary, Bridges, Carolyn B., Barenkamp, Stephen J., Sievert, Dawn M., Srinivasan, Arjun, Doherty, Meg C., McDougal, Linda K., Killgore, George E., Lopatin, Uri A., Coffman, Rebecca, MacDonald, J. Kathryn, McAllister, Sigrid K., Fosheim, Gregory E., Patel, Jean B., McDonald, L. Clifford
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373026/
https://www.ncbi.nlm.nih.gov/pubmed/16707043
http://dx.doi.org/10.3201/eid1206.051141
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author Hageman, Jeffrey C.
Uyeki, Timothy M.
Francis, John S.
Jernigan, Daniel B.
Wheeler, J. Gary
Bridges, Carolyn B.
Barenkamp, Stephen J.
Sievert, Dawn M.
Srinivasan, Arjun
Doherty, Meg C.
McDougal, Linda K.
Killgore, George E.
Lopatin, Uri A.
Coffman, Rebecca
MacDonald, J. Kathryn
McAllister, Sigrid K.
Fosheim, Gregory E.
Patel, Jean B.
McDonald, L. Clifford
author_facet Hageman, Jeffrey C.
Uyeki, Timothy M.
Francis, John S.
Jernigan, Daniel B.
Wheeler, J. Gary
Bridges, Carolyn B.
Barenkamp, Stephen J.
Sievert, Dawn M.
Srinivasan, Arjun
Doherty, Meg C.
McDougal, Linda K.
Killgore, George E.
Lopatin, Uri A.
Coffman, Rebecca
MacDonald, J. Kathryn
McAllister, Sigrid K.
Fosheim, Gregory E.
Patel, Jean B.
McDonald, L. Clifford
author_sort Hageman, Jeffrey C.
collection PubMed
description During the 2003–04 influenza season, 17 cases of Staphylococcus aureus community-acquired pneumonia (CAP) were reported from 9 states; 15 (88%) were associated with methicillin-resistant S. aureus (MRSA). The median age of patients was 21 years; 5 (29%) had underlying diseases, and 4 (24%) had risk factors for MRSA. Twelve (71%) had laboratory evidence of influenza virus infection. All but 1 patient, who died on arrival, were hospitalized. Death occurred in 5 (4 with MRSA). S. aureus isolates were available from 13 (76%) patients (11 MRSA). Toxin genes were detected in all isolates; 11 (85%) had only genes for Panton-Valentine leukocidin. All isolates had community-associated pulsed-field gel electrophoresis patterns; all MRSA isolates had the staphylococcal cassette chromosome mec type IVa. In communities with a high prevalence of MRSA, empiric therapy of severe CAP during periods of high influenza activity should include consideration for MRSA.
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spelling pubmed-33730262012-06-13 Severe Community-acquired Pneumonia Due to Staphylococcus aureus, 2003–04 Influenza Season Hageman, Jeffrey C. Uyeki, Timothy M. Francis, John S. Jernigan, Daniel B. Wheeler, J. Gary Bridges, Carolyn B. Barenkamp, Stephen J. Sievert, Dawn M. Srinivasan, Arjun Doherty, Meg C. McDougal, Linda K. Killgore, George E. Lopatin, Uri A. Coffman, Rebecca MacDonald, J. Kathryn McAllister, Sigrid K. Fosheim, Gregory E. Patel, Jean B. McDonald, L. Clifford Emerg Infect Dis Research During the 2003–04 influenza season, 17 cases of Staphylococcus aureus community-acquired pneumonia (CAP) were reported from 9 states; 15 (88%) were associated with methicillin-resistant S. aureus (MRSA). The median age of patients was 21 years; 5 (29%) had underlying diseases, and 4 (24%) had risk factors for MRSA. Twelve (71%) had laboratory evidence of influenza virus infection. All but 1 patient, who died on arrival, were hospitalized. Death occurred in 5 (4 with MRSA). S. aureus isolates were available from 13 (76%) patients (11 MRSA). Toxin genes were detected in all isolates; 11 (85%) had only genes for Panton-Valentine leukocidin. All isolates had community-associated pulsed-field gel electrophoresis patterns; all MRSA isolates had the staphylococcal cassette chromosome mec type IVa. In communities with a high prevalence of MRSA, empiric therapy of severe CAP during periods of high influenza activity should include consideration for MRSA. Centers for Disease Control and Prevention 2006-06 /pmc/articles/PMC3373026/ /pubmed/16707043 http://dx.doi.org/10.3201/eid1206.051141 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Hageman, Jeffrey C.
Uyeki, Timothy M.
Francis, John S.
Jernigan, Daniel B.
Wheeler, J. Gary
Bridges, Carolyn B.
Barenkamp, Stephen J.
Sievert, Dawn M.
Srinivasan, Arjun
Doherty, Meg C.
McDougal, Linda K.
Killgore, George E.
Lopatin, Uri A.
Coffman, Rebecca
MacDonald, J. Kathryn
McAllister, Sigrid K.
Fosheim, Gregory E.
Patel, Jean B.
McDonald, L. Clifford
Severe Community-acquired Pneumonia Due to Staphylococcus aureus, 2003–04 Influenza Season
title Severe Community-acquired Pneumonia Due to Staphylococcus aureus, 2003–04 Influenza Season
title_full Severe Community-acquired Pneumonia Due to Staphylococcus aureus, 2003–04 Influenza Season
title_fullStr Severe Community-acquired Pneumonia Due to Staphylococcus aureus, 2003–04 Influenza Season
title_full_unstemmed Severe Community-acquired Pneumonia Due to Staphylococcus aureus, 2003–04 Influenza Season
title_short Severe Community-acquired Pneumonia Due to Staphylococcus aureus, 2003–04 Influenza Season
title_sort severe community-acquired pneumonia due to staphylococcus aureus, 2003–04 influenza season
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373026/
https://www.ncbi.nlm.nih.gov/pubmed/16707043
http://dx.doi.org/10.3201/eid1206.051141
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