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Social Behavior and Meningococcal Carriage in British Teenagers

Understanding predisposing factors for meningococcal carriage may identify targets for public health interventions. Before mass vaccination with meningococcal group C conjugate vaccine began in autumn 1999, we took pharyngeal swabs from ≈14,000 UK teenagers and collected information on potential ris...

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Autores principales: MacLennan, Jenny, Kafatos, George, Neal, Keith, Andrews, Nick, Cameron, J. Claire, Roberts, Richard, Evans, Meirion R., Cann, Kathy, Baxter, David N., Maiden, Martin C.J., Stuart, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373034/
https://www.ncbi.nlm.nih.gov/pubmed/16707051
http://dx.doi.org/10.3201/eid1206.051297
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author MacLennan, Jenny
Kafatos, George
Neal, Keith
Andrews, Nick
Cameron, J. Claire
Roberts, Richard
Evans, Meirion R.
Cann, Kathy
Baxter, David N.
Maiden, Martin C.J.
Stuart, James M.
author_facet MacLennan, Jenny
Kafatos, George
Neal, Keith
Andrews, Nick
Cameron, J. Claire
Roberts, Richard
Evans, Meirion R.
Cann, Kathy
Baxter, David N.
Maiden, Martin C.J.
Stuart, James M.
author_sort MacLennan, Jenny
collection PubMed
description Understanding predisposing factors for meningococcal carriage may identify targets for public health interventions. Before mass vaccination with meningococcal group C conjugate vaccine began in autumn 1999, we took pharyngeal swabs from ≈14,000 UK teenagers and collected information on potential risk factors. Neisseria meningitidis was cultured from 2,319 (16.7%) of 13,919 swabs. In multivariable analysis, attendance at pubs/clubs, intimate kissing, and cigarette smoking were each independently and strongly associated with increased risk for meningococcal carriage (p<0.001). Carriage in those with none of these risk factors was 7.8%, compared to 32.8% in those with all 3. Passive smoking was also linked to higher risk for carriage, but age, sex, social deprivation, home crowding, or school characteristics had little or no effect. Social behavior, rather than age or sex, can explain the higher frequency of meningococcal carriage among teenagers. A ban on smoking in public places may reduce risk for transmission.
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spelling pubmed-33730342012-06-13 Social Behavior and Meningococcal Carriage in British Teenagers MacLennan, Jenny Kafatos, George Neal, Keith Andrews, Nick Cameron, J. Claire Roberts, Richard Evans, Meirion R. Cann, Kathy Baxter, David N. Maiden, Martin C.J. Stuart, James M. Emerg Infect Dis Research Understanding predisposing factors for meningococcal carriage may identify targets for public health interventions. Before mass vaccination with meningococcal group C conjugate vaccine began in autumn 1999, we took pharyngeal swabs from ≈14,000 UK teenagers and collected information on potential risk factors. Neisseria meningitidis was cultured from 2,319 (16.7%) of 13,919 swabs. In multivariable analysis, attendance at pubs/clubs, intimate kissing, and cigarette smoking were each independently and strongly associated with increased risk for meningococcal carriage (p<0.001). Carriage in those with none of these risk factors was 7.8%, compared to 32.8% in those with all 3. Passive smoking was also linked to higher risk for carriage, but age, sex, social deprivation, home crowding, or school characteristics had little or no effect. Social behavior, rather than age or sex, can explain the higher frequency of meningococcal carriage among teenagers. A ban on smoking in public places may reduce risk for transmission. Centers for Disease Control and Prevention 2006-06 /pmc/articles/PMC3373034/ /pubmed/16707051 http://dx.doi.org/10.3201/eid1206.051297 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
MacLennan, Jenny
Kafatos, George
Neal, Keith
Andrews, Nick
Cameron, J. Claire
Roberts, Richard
Evans, Meirion R.
Cann, Kathy
Baxter, David N.
Maiden, Martin C.J.
Stuart, James M.
Social Behavior and Meningococcal Carriage in British Teenagers
title Social Behavior and Meningococcal Carriage in British Teenagers
title_full Social Behavior and Meningococcal Carriage in British Teenagers
title_fullStr Social Behavior and Meningococcal Carriage in British Teenagers
title_full_unstemmed Social Behavior and Meningococcal Carriage in British Teenagers
title_short Social Behavior and Meningococcal Carriage in British Teenagers
title_sort social behavior and meningococcal carriage in british teenagers
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373034/
https://www.ncbi.nlm.nih.gov/pubmed/16707051
http://dx.doi.org/10.3201/eid1206.051297
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