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The Expanding Family of Bone Marrow Homing Factors for Hematopoietic Stem Cells: Stromal Derived Factor 1 Is Not the Only Player in the Game

The α-chemokine stromal derived factor 1 (SDF-1), which binds to the CXCR4 and CXCR7 receptors, directs migration and homing of CXCR4(+) hematopoietic stem/progenitor cells (HSPCs) to bone marrow (BM) and plays a crucial role in retention of these cells in stem cell niches. However, this unique role...

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Detalles Bibliográficos
Autores principales: Ratajczak, Mariusz Z., Kim, ChiHwa, Janowska-Wieczorek, Anna, Ratajczak, Janina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific World Journal 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373139/
https://www.ncbi.nlm.nih.gov/pubmed/22701372
http://dx.doi.org/10.1100/2012/758512