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Neutrophil arrest by LFA-1 activation
Lymphocyte function-associated antigen-1 (LFA-1) is a heterodimeric integrin consisting of α(L) (gene name, Itgal) and β(2) (gene name, Itgb2) subunits expressed in all leukocytes. LFA-1 is essential for neutrophil recruitment to inflamed tissue. Activation of LFA-1 by chemokines allows neutrophils...
Autores principales: | Lefort, Craig T., Ley, Klaus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373145/ https://www.ncbi.nlm.nih.gov/pubmed/22701459 http://dx.doi.org/10.3389/fimmu.2012.00157 |
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