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Progression from Sustained BK Viruria to Sustained BK Viremia with Immunosuppression Reduction Is Not Associated with Changes in the Noncoding Control Region of the BK Virus Genome

Changes in the BK virus archetypal noncoding control region (NCCR) have been associated with BK-virus-associated nephropathy (BKVAN). Whether sustained viremia, a surrogate for BKVAN, is associated with significant changes in the BK-NCCR is unknown. We performed PCR amplification and sequencing of (...

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Detalles Bibliográficos
Autores principales: Memon, Imran A., Parikh, Bijal A., Gaudreault-Keener, Monique, Skelton, Rebecca, Storch, Gregory A., Brennan, Daniel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373156/
https://www.ncbi.nlm.nih.gov/pubmed/22701777
http://dx.doi.org/10.1155/2012/761283