Cargando…

Very low levels of HDL cholesterol and atherosclerosis, a variable relationship – a review of LCAT deficiency

A number of epidemiological and clinical studies have demonstrated that plasma high-density lipoprotein (HDL) level is a strong inverse predictor of cardiovascular events. HDL is believed to retard the formation of atherosclerotic lesions by removing excess cholesterol from cells and preventing endo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Savel, Julia, Lafitte, Marianne, Pucheu, Yann, Pradeau, Vincent, Tabarin, Antoine, Couffinhal, Thierry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2012
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373316/ https://www.ncbi.nlm.nih.gov/pubmed/22701329 http://dx.doi.org/10.2147/VHRM.S29985

Ejemplares similares

rHDL modeling and the anchoring mechanism of LCAT activation
por: Laurenzi, Tommaso, et al.
Publicado: (2020)

An unusual presentation of LCAT deficiency as nephrotic syndrome with normal serum HDL-C level
por: Balwani, Manish R, et al.
Publicado: (2016)

Familial lecithin-cholesterol acyltransferase (LCAT) deficiency; a differential of proteinuria
por: Althaf, Mohammed Mahdi, et al.
Publicado: (2015)

Two novel variants in the lecithin:cholesterol acyltransferase gene resulted in classic LCAT deficiency
por: Fistrek Prlic, Margareta, et al.
Publicado: (2022)

Lipid Profile Rather Than the LCAT Mutation Explains Renal Disease in Familial LCAT Deficiency
por: Lamiquiz-Moneo, Itziar, et al.
Publicado: (2019)

Metabolism of PLTP, CETP, and LCAT on multiple HDL sizes using the Orbitrap Fusion Lumos
por: Singh, Sasha A., et al.
Publicado: (2021)

First-in-human autologous implantation of genetically modified adipocytes expressing LCAT for the treatment of familial LCAT deficiency
por: Aso, Masayuki, et al.
Publicado: (2022)

Current Status of Familial LCAT Deficiency in Japan
por: Kuroda, Masayuki, et al.
Publicado: (2021)

Adrenal Function in Females with Low Plasma HDL-C Due to Mutations in ABCA1 and LCAT
por: Bochem, Andrea E., et al.
Publicado: (2014)

Allele-specific enhancers mediate associations between LCAT and ABCA1 polymorphisms and HDL metabolism
por: Howard, Alicia D., et al.
Publicado: (2019)

Lipoprotein X Causes Renal Disease in LCAT Deficiency
por: Ossoli, Alice, et al.
Publicado: (2016)

Novel missense variants in LCAT and APOB genes in an Italian kindred with familial lecithin:cholesterol acyltransferase deficiency and hypobetalipoproteinemia
por: Conca, Paola, et al.
Publicado: (2012)

An apoA-I mimetic peptide increases LCAT activity in mice through increasing HDL concentration
por: Chen, Xun, et al.
Publicado: (2009)

HDL Improves Cholesterol and Glucose Homeostasis and Reduces Atherosclerosis in Diabetes-Associated Atherosclerosis
por: Di Bartolo, Belinda A., et al.
Publicado: (2021)

The effect of weight loss on HDL subfractions and LCAT activity in two genotypes of APOA-II -265T>C polymorphism
por: Moradi, Masoumeh, et al.
Publicado: (2017)

Lack of Correlation of Plasma HDL With Fecal Cholesterol and Plasma Cholesterol Efflux Capacity Suggests Importance of HDL Functionality in Attenuation of Atherosclerosis
por: Srivastava, Neelam, et al.
Publicado: (2018)

Low Plasma Lecithin: Cholesterol Acyltransferase (LCAT) Concentration Predicts Chronic Kidney Disease
por: Baragetti, Andrea, et al.
Publicado: (2020)

LCAT, ApoD, and ApoA1 Expression and Review of Cholesterol Deposition in the Cornea
por: Flores, Rhonda, et al.
Publicado: (2019)

Roles of the Metabolic Syndrome, HDL Cholesterol, and Coronary Atherosclerosis in Subclinical Inflammation
por: Rein, Philipp, et al.
Publicado: (2010)

Triglyceride/HDL-Cholesterol Ratio as an Index of Intracranial Atherosclerosis in Nonstroke Individuals
por: Woo, Min-Hee, et al.
Publicado: (2021)

LCAT deficiency: a systematic review with the clinical and genetic description of Mexican kindred
por: Mehta, Roopa, et al.
Publicado: (2021)

Two novel mutations of lecithin:cholesterol acyltransferase (LCAT) gene and the influence of APOE genotypes on clinical manifestations
por: Katayama, Akihiro, et al.
Publicado: (2011)

Association Between Lipids, Lipoproteins Composition of HDL Particles and Triglyceride-Rich Lipoproteins, and LCAT and CETP Activity in Post-renal Transplant Patients
por: Kimak, Elżbieta, et al.
Publicado: (2013)

P1642: CLONAL HEMATOPOIESIS OF INDETERMINATE POTENTIAL ARE ASSOCIATED WITH INCREASED NETOSIS IN PATIENTS WITH CARDIOVASCULAR EVENTS
por: Marti, Severine, et al.
Publicado: (2023)

Abnormal Lipoproteins Trigger Oxidative Stress-Mediated Apoptosis of Renal Cells in LCAT Deficiency
por: Gomaraschi, Monica, et al.
Publicado: (2023)

HDL Size is More Accurate than HDL Cholesterol to Predict Carotid Subclinical Atherosclerosis in Individuals Classified as Low Cardiovascular Risk
por: Parra, Eliane Soler, et al.
Publicado: (2014)

Therapeutic FGF19 promotes HDL biogenesis and transhepatic cholesterol efflux to prevent atherosclerosis
por: Zhou, Mei, et al.
Publicado: (2019)

HDL Cholesterol Story Is Dead: Long Live HDL!
por: Simha, Vinaya, et al.
Publicado: (2016)

Higher non-HDL-cholesterol to HDL-cholesterol ratio linked with increased nonalcoholic steatohepatitis
por: Wang, Dianhui, et al.
Publicado: (2018)

Levels of Cholesterol in Small LDL Particles Predict Atherosclerosis Progression and Incident CHD in the HDL-Atherosclerosis Treatment Study (HATS)
por: Williams, Paul T., et al.
Publicado: (2013)

HDL, Atherosclerosis, and Emerging Therapies
por: Hafiane, Anouar, et al.
Publicado: (2013)

Associations between LDL/HDL-cholesterol ratio and thoracic and abdominal aortic atherosclerosis assessed by MRI
por: Momiyama, Yukihiko, et al.
Publicado: (2012)

HDL cholesterol efflux capacity in rheumatoid arthritis patients: contributing factors and relationship with subclinical atherosclerosis
por: Tejera-Segura, Beatriz, et al.
Publicado: (2017)

Toxoplasma gondii LCAT Primarily Contributes to Tachyzoite Egress
por: Schultz, Aric J., et al.
Publicado: (2018)

Hypolipidemic effect and activation of Lecithin Cholesterol Acyl Transferase (LCAT) by aqueous extract of Spirulina platensis during toxicological investigation
por: Ama Moor, Vicky Jocelyne, et al.
Publicado: (2017)

Raising HDL cholesterol in women
por: Eapen, Danny J, et al.
Publicado: (2010)

Nascent HDL (High-Density Lipoprotein) Discs Carry Cholesterol to HDL Spheres: Effects of HDL Particle Remodeling on Cholesterol Efflux
por: Navdaev, Alexei V., et al.
Publicado: (2020)

Plasma FA composition in familial LCAT deficiency indicates SOAT2-derived cholesteryl ester formation in humans
por: Pavanello, Chiara, et al.
Publicado: (2022)

Non-HDL-cholesterol to HDL-cholesterol ratio is a better predictor of new-onset non-alcoholic fatty liver disease than non-HDL-cholesterol: a cohort study
por: Wang, Kun, et al.
Publicado: (2018)

Standardization of Apolipoprotein B, LDL‐Cholesterol, and Non‐HDL‐Cholesterol
por: Contois, John H., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_khqi56scck59r14ufucvj7qlh8