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Control of progesterone receptor transcriptional synergy by SUMOylation and deSUMOylation
BACKGROUND: Covalent modification of nuclear receptors by the Small Ubiquitin-like Modifier (SUMO) is dynamically regulated by competing conjugation/deconjugation steps that modulate their overall transcriptional activity. SUMO conjugation of progesterone receptors (PRs) at the N-terminal lysine (K)...
Autores principales: | Abdel-Hafiz, Hany A, Horwitz, Kathryn B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373386/ https://www.ncbi.nlm.nih.gov/pubmed/22439847 http://dx.doi.org/10.1186/1471-2199-13-10 |
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