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GPR158/179 regulate G protein signaling by controlling localization and activity of the RGS7 complexes

The extent and temporal characteristics of G protein–coupled receptor (GPCR) signaling are shaped by the regulator of G protein signaling (RGS) proteins, which promote G protein deactivation. With hundreds of GPCRs and dozens of RGS proteins, compartmentalization plays a key role in establishing sig...

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Detalles Bibliográficos
Autores principales:	Orlandi, Cesare, Posokhova, Ekaterina, Masuho, Ikuo, Ray, Thomas A., Hasan, Nazarul, Gregg, Ronald G., Martemyanov, Kirill A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2012
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373406/ https://www.ncbi.nlm.nih.gov/pubmed/22689652 http://dx.doi.org/10.1083/jcb.201202123

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