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2D protrusion but not motility predicts growth factor–induced cancer cell migration in 3D collagen

Growth factor–induced migration is a critical step in the dissemination and metastasis of solid tumors. Although differences in properties characterizing cell migration on two-dimensional (2D) substrata versus within three-dimensional (3D) matrices have been noted for particular growth factor stimul...

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Detalles Bibliográficos
Autores principales:	Meyer, Aaron S., Hughes-Alford, Shannon K., Kay, Jennifer E., Castillo, Amalchi, Wells, Alan, Gertler, Frank B., Lauffenburger, Douglas A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2012
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373410/ https://www.ncbi.nlm.nih.gov/pubmed/22665521 http://dx.doi.org/10.1083/jcb.201201003

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