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Intracellular Pathogen Leishmania donovani Activates Hypoxia Inducible Factor-1 by Dual Mechanism for Survival Advantage within Macrophage

Recent evidence established a crucial role for mammalian oxygen sensing transcription factor hypoxia inducible factor-1 (HIF-1) in innate immunity against intracellular pathogens. In response to most of these pathogens host phagocytes increase transcription of HIF-1α, the regulatory component of HIF...

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Detalles Bibliográficos
Autores principales:	Singh, Amit Kumar, Mukhopadhyay, Chaitali, Biswas, Sudipta, Singh, Vandana Kumari, Mukhopadhyay, Chinmay K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373497/ https://www.ncbi.nlm.nih.gov/pubmed/22701652 http://dx.doi.org/10.1371/journal.pone.0038489

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