FGFR1-Induced Epithelial to Mesenchymal Transition through MAPK/PLCγ/COX-2-Mediated Mechanisms

Tumour invasion and metastasis is the most common cause of death from cancer. For epithelial cells to invade surrounding tissues and metastasise, an epithelial-mesenchymal transition (EMT) is required. We have demonstrated that FGFR1 expression is increased in bladder cancer and that activation of F...

Descripción completa

Detalles Bibliográficos
Autores principales: Tomlinson, Darren C., Baxter, Euan W., Loadman, Paul M., Hull, Mark A., Knowles, Margaret A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373505/
https://www.ncbi.nlm.nih.gov/pubmed/22701738
http://dx.doi.org/10.1371/journal.pone.0038972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373505/
https://www.ncbi.nlm.nih.gov/pubmed/22701738
http://dx.doi.org/10.1371/journal.pone.0038972

Ejemplares similares