Cargando…
An exclusively dopamine secreting paraganglioma in the retroperitoneum: a first clinical case in Korea
Exclusively dopamine producing retroperitoneal paragangliomas are extremely rare. We have experienced the first Korean case managed successfully based on the proper evaluation. A 26-year-old female patient came to our attention after the accidental detection of an adrenal mass. She had no symptoms a...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Surgical Society
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373991/ https://www.ncbi.nlm.nih.gov/pubmed/22708103 http://dx.doi.org/10.4174/jkss.2012.82.6.389 |
_version_ | 1782235585582202880 |
---|---|
author | Yi, Jin Wook Oh, Eun Mee Lee, Kyu Eun Choi, June Young Koo, Do Hoon Kim, Kyung Joo Jung, Kyeong-Cheon Kim, Seong-Yeon Youn, Yeo-Kyu |
author_facet | Yi, Jin Wook Oh, Eun Mee Lee, Kyu Eun Choi, June Young Koo, Do Hoon Kim, Kyung Joo Jung, Kyeong-Cheon Kim, Seong-Yeon Youn, Yeo-Kyu |
author_sort | Yi, Jin Wook |
collection | PubMed |
description | Exclusively dopamine producing retroperitoneal paragangliomas are extremely rare. We have experienced the first Korean case managed successfully based on the proper evaluation. A 26-year-old female patient came to our attention after the accidental detection of an adrenal mass. She had no symptoms and denied any family history. Laboratory evaluations were normal but serum dopamine (425 ng/L) and 24-hour urine dopamine levels (1,565.3 µg/day) were elevated. She underwent laparoscopic right adrenalectomy. Histopathological diagnosis was a paraganglioma. After operation, dopamine levels in serum and 24-hour urine dropped to 0.09 ng/L and 388.4 µg/day. Dopamine producing paraganglioma elicit no clinical symptoms. Only the dopamine level is elevated in serum and 24-hour urine samples. Surgical resection without using preoperative alpha blockage is the treatment of choice. The prognosis for patients with this tumor tends to be poor because the diagnosis is usually delayed due to lack of symptoms. |
format | Online Article Text |
id | pubmed-3373991 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | The Korean Surgical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-33739912012-06-15 An exclusively dopamine secreting paraganglioma in the retroperitoneum: a first clinical case in Korea Yi, Jin Wook Oh, Eun Mee Lee, Kyu Eun Choi, June Young Koo, Do Hoon Kim, Kyung Joo Jung, Kyeong-Cheon Kim, Seong-Yeon Youn, Yeo-Kyu J Korean Surg Soc Case Report Exclusively dopamine producing retroperitoneal paragangliomas are extremely rare. We have experienced the first Korean case managed successfully based on the proper evaluation. A 26-year-old female patient came to our attention after the accidental detection of an adrenal mass. She had no symptoms and denied any family history. Laboratory evaluations were normal but serum dopamine (425 ng/L) and 24-hour urine dopamine levels (1,565.3 µg/day) were elevated. She underwent laparoscopic right adrenalectomy. Histopathological diagnosis was a paraganglioma. After operation, dopamine levels in serum and 24-hour urine dropped to 0.09 ng/L and 388.4 µg/day. Dopamine producing paraganglioma elicit no clinical symptoms. Only the dopamine level is elevated in serum and 24-hour urine samples. Surgical resection without using preoperative alpha blockage is the treatment of choice. The prognosis for patients with this tumor tends to be poor because the diagnosis is usually delayed due to lack of symptoms. The Korean Surgical Society 2012-06 2012-05-29 /pmc/articles/PMC3373991/ /pubmed/22708103 http://dx.doi.org/10.4174/jkss.2012.82.6.389 Text en Copyright © 2012, the Korean Surgical Society http://creativecommons.org/licenses/by-nc/3.0 Journal of the Korean Surgical Society is an Open Access Journal. All articles are distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Yi, Jin Wook Oh, Eun Mee Lee, Kyu Eun Choi, June Young Koo, Do Hoon Kim, Kyung Joo Jung, Kyeong-Cheon Kim, Seong-Yeon Youn, Yeo-Kyu An exclusively dopamine secreting paraganglioma in the retroperitoneum: a first clinical case in Korea |
title | An exclusively dopamine secreting paraganglioma in the retroperitoneum: a first clinical case in Korea |
title_full | An exclusively dopamine secreting paraganglioma in the retroperitoneum: a first clinical case in Korea |
title_fullStr | An exclusively dopamine secreting paraganglioma in the retroperitoneum: a first clinical case in Korea |
title_full_unstemmed | An exclusively dopamine secreting paraganglioma in the retroperitoneum: a first clinical case in Korea |
title_short | An exclusively dopamine secreting paraganglioma in the retroperitoneum: a first clinical case in Korea |
title_sort | exclusively dopamine secreting paraganglioma in the retroperitoneum: a first clinical case in korea |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373991/ https://www.ncbi.nlm.nih.gov/pubmed/22708103 http://dx.doi.org/10.4174/jkss.2012.82.6.389 |
work_keys_str_mv | AT yijinwook anexclusivelydopaminesecretingparagangliomaintheretroperitoneumafirstclinicalcaseinkorea AT oheunmee anexclusivelydopaminesecretingparagangliomaintheretroperitoneumafirstclinicalcaseinkorea AT leekyueun anexclusivelydopaminesecretingparagangliomaintheretroperitoneumafirstclinicalcaseinkorea AT choijuneyoung anexclusivelydopaminesecretingparagangliomaintheretroperitoneumafirstclinicalcaseinkorea AT koodohoon anexclusivelydopaminesecretingparagangliomaintheretroperitoneumafirstclinicalcaseinkorea AT kimkyungjoo anexclusivelydopaminesecretingparagangliomaintheretroperitoneumafirstclinicalcaseinkorea AT jungkyeongcheon anexclusivelydopaminesecretingparagangliomaintheretroperitoneumafirstclinicalcaseinkorea AT kimseongyeon anexclusivelydopaminesecretingparagangliomaintheretroperitoneumafirstclinicalcaseinkorea AT younyeokyu anexclusivelydopaminesecretingparagangliomaintheretroperitoneumafirstclinicalcaseinkorea AT yijinwook exclusivelydopaminesecretingparagangliomaintheretroperitoneumafirstclinicalcaseinkorea AT oheunmee exclusivelydopaminesecretingparagangliomaintheretroperitoneumafirstclinicalcaseinkorea AT leekyueun exclusivelydopaminesecretingparagangliomaintheretroperitoneumafirstclinicalcaseinkorea AT choijuneyoung exclusivelydopaminesecretingparagangliomaintheretroperitoneumafirstclinicalcaseinkorea AT koodohoon exclusivelydopaminesecretingparagangliomaintheretroperitoneumafirstclinicalcaseinkorea AT kimkyungjoo exclusivelydopaminesecretingparagangliomaintheretroperitoneumafirstclinicalcaseinkorea AT jungkyeongcheon exclusivelydopaminesecretingparagangliomaintheretroperitoneumafirstclinicalcaseinkorea AT kimseongyeon exclusivelydopaminesecretingparagangliomaintheretroperitoneumafirstclinicalcaseinkorea AT younyeokyu exclusivelydopaminesecretingparagangliomaintheretroperitoneumafirstclinicalcaseinkorea |