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An exclusively dopamine secreting paraganglioma in the retroperitoneum: a first clinical case in Korea

Exclusively dopamine producing retroperitoneal paragangliomas are extremely rare. We have experienced the first Korean case managed successfully based on the proper evaluation. A 26-year-old female patient came to our attention after the accidental detection of an adrenal mass. She had no symptoms a...

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Autores principales: Yi, Jin Wook, Oh, Eun Mee, Lee, Kyu Eun, Choi, June Young, Koo, Do Hoon, Kim, Kyung Joo, Jung, Kyeong-Cheon, Kim, Seong-Yeon, Youn, Yeo-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Surgical Society 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373991/
https://www.ncbi.nlm.nih.gov/pubmed/22708103
http://dx.doi.org/10.4174/jkss.2012.82.6.389
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author Yi, Jin Wook
Oh, Eun Mee
Lee, Kyu Eun
Choi, June Young
Koo, Do Hoon
Kim, Kyung Joo
Jung, Kyeong-Cheon
Kim, Seong-Yeon
Youn, Yeo-Kyu
author_facet Yi, Jin Wook
Oh, Eun Mee
Lee, Kyu Eun
Choi, June Young
Koo, Do Hoon
Kim, Kyung Joo
Jung, Kyeong-Cheon
Kim, Seong-Yeon
Youn, Yeo-Kyu
author_sort Yi, Jin Wook
collection PubMed
description Exclusively dopamine producing retroperitoneal paragangliomas are extremely rare. We have experienced the first Korean case managed successfully based on the proper evaluation. A 26-year-old female patient came to our attention after the accidental detection of an adrenal mass. She had no symptoms and denied any family history. Laboratory evaluations were normal but serum dopamine (425 ng/L) and 24-hour urine dopamine levels (1,565.3 µg/day) were elevated. She underwent laparoscopic right adrenalectomy. Histopathological diagnosis was a paraganglioma. After operation, dopamine levels in serum and 24-hour urine dropped to 0.09 ng/L and 388.4 µg/day. Dopamine producing paraganglioma elicit no clinical symptoms. Only the dopamine level is elevated in serum and 24-hour urine samples. Surgical resection without using preoperative alpha blockage is the treatment of choice. The prognosis for patients with this tumor tends to be poor because the diagnosis is usually delayed due to lack of symptoms.
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spelling pubmed-33739912012-06-15 An exclusively dopamine secreting paraganglioma in the retroperitoneum: a first clinical case in Korea Yi, Jin Wook Oh, Eun Mee Lee, Kyu Eun Choi, June Young Koo, Do Hoon Kim, Kyung Joo Jung, Kyeong-Cheon Kim, Seong-Yeon Youn, Yeo-Kyu J Korean Surg Soc Case Report Exclusively dopamine producing retroperitoneal paragangliomas are extremely rare. We have experienced the first Korean case managed successfully based on the proper evaluation. A 26-year-old female patient came to our attention after the accidental detection of an adrenal mass. She had no symptoms and denied any family history. Laboratory evaluations were normal but serum dopamine (425 ng/L) and 24-hour urine dopamine levels (1,565.3 µg/day) were elevated. She underwent laparoscopic right adrenalectomy. Histopathological diagnosis was a paraganglioma. After operation, dopamine levels in serum and 24-hour urine dropped to 0.09 ng/L and 388.4 µg/day. Dopamine producing paraganglioma elicit no clinical symptoms. Only the dopamine level is elevated in serum and 24-hour urine samples. Surgical resection without using preoperative alpha blockage is the treatment of choice. The prognosis for patients with this tumor tends to be poor because the diagnosis is usually delayed due to lack of symptoms. The Korean Surgical Society 2012-06 2012-05-29 /pmc/articles/PMC3373991/ /pubmed/22708103 http://dx.doi.org/10.4174/jkss.2012.82.6.389 Text en Copyright © 2012, the Korean Surgical Society http://creativecommons.org/licenses/by-nc/3.0 Journal of the Korean Surgical Society is an Open Access Journal. All articles are distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Yi, Jin Wook
Oh, Eun Mee
Lee, Kyu Eun
Choi, June Young
Koo, Do Hoon
Kim, Kyung Joo
Jung, Kyeong-Cheon
Kim, Seong-Yeon
Youn, Yeo-Kyu
An exclusively dopamine secreting paraganglioma in the retroperitoneum: a first clinical case in Korea
title An exclusively dopamine secreting paraganglioma in the retroperitoneum: a first clinical case in Korea
title_full An exclusively dopamine secreting paraganglioma in the retroperitoneum: a first clinical case in Korea
title_fullStr An exclusively dopamine secreting paraganglioma in the retroperitoneum: a first clinical case in Korea
title_full_unstemmed An exclusively dopamine secreting paraganglioma in the retroperitoneum: a first clinical case in Korea
title_short An exclusively dopamine secreting paraganglioma in the retroperitoneum: a first clinical case in Korea
title_sort exclusively dopamine secreting paraganglioma in the retroperitoneum: a first clinical case in korea
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373991/
https://www.ncbi.nlm.nih.gov/pubmed/22708103
http://dx.doi.org/10.4174/jkss.2012.82.6.389
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