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Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters
Despite much research, our understanding of the rules by which cis-regulatory sequences are translated into expression levels is still lacking. We devised a method for obtaining parallel and highly accurate expression measurements of thousands of fully designed promoters, and applied it to measure t...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374032/ https://www.ncbi.nlm.nih.gov/pubmed/22609971 http://dx.doi.org/10.1038/nbt.2205 |