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Increased concentrations of both NMDA receptor co-agonists d-serine and glycine in global ischemia: a potential novel treatment target for perinatal asphyxia
Worldwide, perinatal asphyxia is an important cause of morbidity and mortality among term-born children. Overactivation of the N-methyl-d-aspartate receptor (NMDAr) plays a central role in the pathogenesis of cerebral hypoxia–ischemia, but the role of both endogenous NMDAr co-agonists d-serine and g...
Autores principales: | Fuchs, Sabine A., Peeters-Scholte, Cacha M. P. C. D., de Barse, Martina M. J., Roeleveld, Martin W., Klomp, Leo W. J., Berger, Ruud, de Koning, Tom J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374112/ https://www.ncbi.nlm.nih.gov/pubmed/21947661 http://dx.doi.org/10.1007/s00726-011-1086-9 |
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