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Synaptic Polarity Depends on Phosphatidylinositol Signaling Regulated by myo-Inositol Monophosphatase in Caenorhabditis elegans

Although neurons are highly polarized, how neuronal polarity is generated remains poorly understood. An evolutionarily conserved inositol-producing enzyme myo-inositol monophosphatase (IMPase) is essential for polarized localization of synaptic molecules in Caenorhabditis elegans and can be inhibite...

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Detalles Bibliográficos
Autores principales: Kimata, Tsubasa, Tanizawa, Yoshinori, Can, Yoko, Ikeda, Shingo, Kuhara, Atsushi, Mori, Ikue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374314/
https://www.ncbi.nlm.nih.gov/pubmed/22446320
http://dx.doi.org/10.1534/genetics.111.137844