Cargando…

Uncovering potential Drug Targets for Tuberculosis using Protein Networks

The emergence of HIV-TB co-infection and multi-drug resistant strains of Mycobacterium tuberculosis (Mtb) drive the need for new therapeutics against the infectious disease tuberculosis. Among the reported putative TB targets in the literature, the identification and characterization of the most pro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Raman, Mohana Priya, Singh, Sachidanand, Devi, Ponnuswamy Renuka, Velmurugan, Devadasan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Biomedical Informatics 2012
Materias:	Hypothesis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374368/ https://www.ncbi.nlm.nih.gov/pubmed/22715308 http://dx.doi.org/10.6026/97320630008403

Ejemplares similares

Designing of Protein Kinase C β-II Inhibitors against Diabetic complications: Structure Based Drug Design, Induced Fit docking and analysis of active site conformational changes
por: Vijayakumar, Balakrishnan, et al.
Publicado: (2012)

Insilico analysis and molecular docking of resuscitation promoting factor B (RpfB) protein of Mycobacterium tuberculosis
por: Mylliemngap, Baphilinia Jones, et al.
Publicado: (2012)

3D-QSAR studies on fluroquinolones derivatives as inhibitors for tuberculosis
por: Bhattacharjee, Atanu, et al.
Publicado: (2012)

Docking-based virtual screening of known drugs against murE of Mycobacterium tuberculosis towards repurposing for TB
por: Brindha, Sridharan, et al.
Publicado: (2016)

Structure prediction of Bestrophin for the induced - fit docking of anthocyanins
por: Priya, Sathyan Sri Lavvanya, et al.
Publicado: (2012)

Selection of an improved HDAC8 inhibitor through structure-based drug design
por: Vijayakumar, Balakrishnan, et al.
Publicado: (2011)

Structure based design of compounds from natural sources for diabetes and inflammation
por: Suhitha, Sivasubramanian, et al.
Publicado: (2012)

Active compound from the leaves of Vitex negundo L. shows anti-inflammatory activity with evidence of inhibition for secretory Phospholipase A(2) through molecular docking
por: Vinuchakkaravarthy, Thangaraj, et al.
Publicado: (2011)

Exploring GpG bases next to anticodon in tRNA subsets
por: Srinivasan, Thangavelu, et al.
Publicado: (2013)

Insights from the protein-protein interaction network analysis of Mycobacterium tuberculosis toxin-antitoxin systems
por: Thakur, Zoozeal, et al.
Publicado: (2017)

Exploration of Sitagliptin as a potential inhibitor for the M1 Alanine aminopeptidase enzyme in Plasmodium falciparum using computational docking
por: Krishnamoorthy, Mohana, et al.
Publicado: (2013)

A ClpP protein model as tuberculosis target for screening marine compounds
por: Tiwari, Abhilasha, et al.
Publicado: (2010)

Dataset of potential targets for Mycobacterium tuberculosis H37Rv through comparative genome analysis
por: Asif, Siddiqui M, et al.
Publicado: (2009)

Resistome analysis of Mycobacterium tuberculosis: Identification of aminoglycoside 2'-Nacetyltransferase (AAC) as co-target for drug desigining
por: Joshi, Rakesh S, et al.
Publicado: (2013)

Comparative protein modeling of spermidine synthase from Plasmodium falciparum: A potential target for anti-malarial drug therapy
por: Reddy, Duvvuru Muni Rajasekhara
Publicado: (2006)

Potential therapeutic drug target identification in Community Acquired-Methicillin Resistant Staphylococcus aureus (CA-MRSA) using computational analysis
por: Yadav, Pramod Kumar, et al.
Publicado: (2012)

In Silico Subtractive Proteomics Approach for Identification of Potential Drug Targets in Staphylococcus saprophyticus
por: Shahid, Farah, et al.
Publicado: (2020)

Insights from the molecular docking of withanolide derivatives to the target protein PknG from Mycobacterium tuberculosis
por: Santhi, Natchimuthu, et al.
Publicado: (2011)

A two-step drug repositioning method based on a protein-protein interaction network of genes shared by two diseases and the similarity of drugs
por: Fukuoka, Yutaka, et al.
Publicado: (2013)

CXCL12 in Pancreatic Cancer: Its Function and Potential as a Therapeutic Drug Target
por: Malik, Shivani, et al.
Publicado: (2021)

In silico identification and characterization of a hypothetical protein of Mycobacterium tuberculosis EAI5 as a potential virulent factor
por: Gupta, Debdoot, et al.
Publicado: (2016)

Identification of miRNAs in C. roseus and their potential targets
por: Omer, Ankur, et al.
Publicado: (2012)

Molecular docking of azole drugs and their analogs on CYP121 of Mycobacterium tuberculosis
por: Sundaramurthi, Jagadish Chandrabose, et al.
Publicado: (2011)

Computational screening of molecular targets in Plasmodium for novel non resistant anti-malarial drugs
por: Singh, Neera, et al.
Publicado: (2009)

Structurebased drug design and AutoDock study of potential protein tyrosine kinase inhibitors.
por: Ali, Hamed Ismail, et al.
Publicado: (2011)

Docking studies and network analyses reveal capacity of compounds from Kandelia rheedii to strengthen cellular immunity by interacting with host proteins during tuberculosis infection
por: Zaman, Aubhishek
Publicado: (2012)

Structure based drug designing of a novel antiflaviviral inhibitor for nonstructural 3 protein
por: Jitendra, Singh, et al.
Publicado: (2011)

Identification of potential leads against 4-hydroxytetrahydrodipicolinate synthase from Mycobacterium tuberculosis
por: Rehman, Ajijur, et al.
Publicado: (2016)

Metabolic pathway analysis and molecular docking analysis for identification of putative drug targets in Toxoplasma gondii: novel approach
por: Gautam, Budhayash, et al.
Publicado: (2012)

Identification of glutamate ABC-Transporter component in Clostridium perfringens as a putative drug target
por: Bhatia, Bharti, et al.
Publicado: (2014)

Identification of potential targets in Staphylococcus aureus N315 using computer aided protein data analysis
por: Hossain, Mehjabeen, et al.
Publicado: (2013)

Choke point analysis of metabolic pathways in E.histolytica: A computational approach for drug target identification
por: Singh, Shailza, et al.
Publicado: (2007)

in silico analyses of metabolic pathway and protein interaction network for identification of next gen therapeutic targets in Chlamydophila pneumoniae
por: Ravindranath, Bilachi S, et al.
Publicado: (2013)

Identification and characterization of sodium and chloride-dependent gamma-aminobutyric acid (GABA) transporters from eukaryotic pathogens as a potential drug target
por: Otarigho, Benson, et al.
Publicado: (2018)

Identification of membrane associated drug targets in Borrelia burgdorferi ZS7- subtractive genomics approach
por: Madagi, Shivkumar, et al.
Publicado: (2011)

Computational finding of potential inhibitor for Cytochrome P450 Mono-oxygenases Enzyme of Mycobacterium tuberculosis
por: Sharma, Ashwani, et al.
Publicado: (2012)

Homology modeling, docking studies and functional analysis of various azoreductase accessory interacting proteins of Nostoc sp.PCC7120
por: Philem, Priyadarshini Devi, et al.
Publicado: (2012)

A rapid identification technique for drug-resistant Mycobacterium tuberculosis isolates using mismatch specific cleavage enzyme
por: Jaramillo, Luis, et al.
Publicado: (2018)

Elucidation of Prebiotics, Probiotics, Postbiotics, and Target from Gut Microbiota to Alleviate Obesity via Network Pharmacology Study
por: Oh, Ki-Kwang, et al.
Publicado: (2022)

A comprehensive molecular interaction map for Hepatitis B virus and drug designing of a novel inhibitor for Hepatitis B X protein
por: Jitendra, Singh, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_coii5cn8l37gdvcai9sihtn9ri