Escherichia coli: Great Diversity around a Common Core

The 2011 Escherichia coli outbreak in Germany, which resulted in more than 4,000 cases, including 908 cases of hemolytic-uremic syndrome (HUS) and at least 50 deaths, highlighted the genome plasticity of E. coli and the potential for new virulent strains to emerge. The analysis of 170 E. coli genome...

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Autores principales: Moriel, Danilo G., Rosini, Roberto, Seib, Kate L., Serino, Laura, Pizza, Mariagrazia, Rappuoli, Rino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2012
Materias:
Observation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374390/
https://www.ncbi.nlm.nih.gov/pubmed/22669628
http://dx.doi.org/10.1128/mBio.00118-12
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author Moriel, Danilo G.
Rosini, Roberto
Seib, Kate L.
Serino, Laura
Pizza, Mariagrazia
Rappuoli, Rino
author_facet Moriel, Danilo G.
Rosini, Roberto
Seib, Kate L.
Serino, Laura
Pizza, Mariagrazia
Rappuoli, Rino
author_sort Moriel, Danilo G.
collection PubMed
description The 2011 Escherichia coli outbreak in Germany, which resulted in more than 4,000 cases, including 908 cases of hemolytic-uremic syndrome (HUS) and at least 50 deaths, highlighted the genome plasticity of E. coli and the potential for new virulent strains to emerge. The analysis of 170 E. coli genome sequences for the presence of nine previously identified protective extraintestinal pathogenic E. coli antigens suggested the feasibility of a combination vaccine as a universal intervention against all pathogenic E. coli strains.
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spelling pubmed-33743902012-06-13 Escherichia coli: Great Diversity around a Common Core Moriel, Danilo G. Rosini, Roberto Seib, Kate L. Serino, Laura Pizza, Mariagrazia Rappuoli, Rino mBio Observation The 2011 Escherichia coli outbreak in Germany, which resulted in more than 4,000 cases, including 908 cases of hemolytic-uremic syndrome (HUS) and at least 50 deaths, highlighted the genome plasticity of E. coli and the potential for new virulent strains to emerge. The analysis of 170 E. coli genome sequences for the presence of nine previously identified protective extraintestinal pathogenic E. coli antigens suggested the feasibility of a combination vaccine as a universal intervention against all pathogenic E. coli strains. American Society of Microbiology 2012-06-05 /pmc/articles/PMC3374390/ /pubmed/22669628 http://dx.doi.org/10.1128/mBio.00118-12 Text en Copyright © 2012 Moriel et al. http://creativecommons.org/licenses/by-nc-sa/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License (http://creativecommons.org/licenses/by-nc-sa/3.0/) , which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Observation
Moriel, Danilo G.
Rosini, Roberto
Seib, Kate L.
Serino, Laura
Pizza, Mariagrazia
Rappuoli, Rino
Escherichia coli: Great Diversity around a Common Core
title Escherichia coli: Great Diversity around a Common Core
title_full Escherichia coli: Great Diversity around a Common Core
title_fullStr Escherichia coli: Great Diversity around a Common Core
title_full_unstemmed Escherichia coli: Great Diversity around a Common Core
title_short Escherichia coli: Great Diversity around a Common Core
title_sort escherichia coli: great diversity around a common core
topic Observation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374390/
https://www.ncbi.nlm.nih.gov/pubmed/22669628
http://dx.doi.org/10.1128/mBio.00118-12
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