Cargando…

Combined Transfer of Human VEGF165 and HGF Genes Renders Potent Angiogenic Effect in Ischemic Skeletal Muscle

Increased interest in development of combined gene therapy emerges from results of recent clinical trials that indicate good safety yet unexpected low efficacy of “single-gene” administration. Multiple studies showed that vascular endothelial growth factor 165 aminoacid form (VEGF165) and hepatocyte...

Descripción completa

Detalles Bibliográficos
Autores principales:	Makarevich, Pavel, Tsokolaeva, Zoya, Shevelev, Alexander, Rybalkin, Igor, Shevchenko, Evgeny, Beloglazova, Irina, Vlasik, Tatyana, Tkachuk, Vsevolod, Parfyonova, Yelena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374822/ https://www.ncbi.nlm.nih.gov/pubmed/22719942 http://dx.doi.org/10.1371/journal.pone.0038776

Ejemplares similares

Transplantation of modified human adipose derived stromal cells expressing VEGF165 results in more efficient angiogenic response in ischemic skeletal muscle
por: Shevchenko, Evgeny K, et al.
Publicado: (2013)

Angiogenic and pleiotropic effects of VEGF165 and HGF combined gene therapy in a rat model of myocardial infarction
por: Makarevich, Pavel I., et al.
Publicado: (2018)

Therapeutic Angiogenesis by a “Dynamic Duo”: Simultaneous Expression of HGF and VEGF165 by Novel Bicistronic Plasmid Restores Blood Flow in Ischemic Skeletal Muscle
por: Slobodkina, Ekaterina, et al.
Publicado: (2020)

Urokinase-Type Plasminogen Activator Receptor Regulates Prosurvival and Angiogenic Properties of Cardiac Mesenchymal Stromal Cells
por: Dergilev, Konstantin, et al.
Publicado: (2023)

Oligonucleotide Microarrays Identified Potential Regulatory Genes Related to Early Outward Arterial Remodeling Induced by Tissue Plasminogen Activator
por: Plekhanova, Olga, et al.
Publicado: (2019)

Enhanced angiogenesis in ischemic skeletal muscle after transplantation of cell sheets from baculovirus-transduced adipose-derived stromal cells expressing VEGF165
por: Makarevich, Pavel I., et al.
Publicado: (2015)

Transplantation of Adipose Stromal Cell Sheet Producing Hepatocyte Growth Factor Induces Pleiotropic Effect in Ischemic Skeletal Muscle
por: Boldyreva, Maria A., et al.
Publicado: (2019)

Cell Sheet Comprised of Mesenchymal Stromal Cells Overexpressing Stem Cell Factor Promotes Epicardium Activation and Heart Function Improvement in a Rat Model of Myocardium Infarction
por: Dergilev, Konstantin V., et al.
Publicado: (2020)

VEGF(121)b and VEGF(165)b are weakly angiogenic isoforms of VEGF-A
por: Catena, Raúl, et al.
Publicado: (2010)

The Efficacy of HGF/VEGF Gene Therapy for Limb Ischemia in Mice with Impaired Glucose Tolerance: Shift from Angiogenesis to Axonal Growth and Oxidative Potential in Skeletal Muscle
por: Stafeev I, Iurii S., et al.
Publicado: (2022)

Angiogenic Effects of Collagen/Mesoporous Nanoparticle Composite Scaffold Delivering VEGF(165)
por: Kim, Joong-Hyun, et al.
Publicado: (2016)

The endogenous anti-angiogenic VEGF isoform, VEGF(165)b inhibits human tumour growth in mice
por: Rennel, E S, et al.
Publicado: (2008)

C-Kit Cardiac Progenitor Cell Based Cell Sheet Improves Vascularization and Attenuates Cardiac Remodeling following Myocardial Infarction in Rats
por: Dergilev, K., et al.
Publicado: (2018)

New Insight on 2D In Vitro Angiogenesis Models: All That Stretches Is Not a Tube
por: Beloglazova, Irina, et al.
Publicado: (2022)

The splicing factor YBX1 promotes the progression of osteosarcoma by upregulating VEGF(165) and downregulating VEGF(165b)
por: Quan, Bingxuan, et al.
Publicado: (2023)

Disturbed angiogenic activity of adipose-derived stromal cells obtained from patients with coronary artery disease and diabetes mellitus type 2
por: Dzhoyashvili, Nina A, et al.
Publicado: (2014)

Dynamics and implications of circulating anti-angiogenic VEGF-A(165)b isoform in patients with ST-elevation myocardial infarction
por: Hueso, Luisa, et al.
Publicado: (2017)

Expression of Total Vascular Endothelial Growth Factor and the Anti-angiogenic VEGF(165)b Isoform in the Vitreous of Patients with Retinopathy of Prematurity
por: Zhao, Min, et al.
Publicado: (2015)

Angiogenic Modification of Microfibrous Polycaprolactone by pCMV-VEGF165 Plasmid Promotes Local Vascular Growth after Implantation in Rats
por: Klabukov, Ilya, et al.
Publicado: (2023)

The role of VEGF-A(165)b in trophoblast survival
por: Bills, Victoria L, et al.
Publicado: (2014)

Adipose-Derived Stem Cells Stimulate Regeneration of Peripheral Nerves: BDNF Secreted by These Cells Promotes Nerve Healing and Axon Growth De Novo
por: Lopatina, Tatiana, et al.
Publicado: (2011)

Correction: Adipose-Derived Stem Cells Stimulate Regeneration of Peripheral Nerves: BDNF Secreted by These Cells Promotes Nerve Healing and Axon Growth De Novo
por: Lopatina, Tatiana, et al.
Publicado: (2019)

A multiscale computational model predicts distribution of anti-angiogenic isoform VEGF(165b) in peripheral arterial disease in human and mouse
por: Chu, Liang-Hui, et al.
Publicado: (2016)

VEGF, VEGF165b and EG-VEGF expression is specifically related with hormone profile in pituitary adenomas
por: Corlan, Ana Silvia, et al.
Publicado: (2019)

Inhibition of retinal neovascularization by siRNA targeting VEGF(165)
por: Xia, Xiao-bo, et al.
Publicado: (2008)

Systems Pharmacology of VEGF165b in Peripheral Artery Disease
por: Clegg, Lindsay E., et al.
Publicado: (2017)

Levels of vascular endothelial growth factor-A(165b) (VEGF-A(165b)) are elevated in experimental glaucoma
por: Ergorul, Ceren, et al.
Publicado: (2008)

Effects of receptor tyrosine kinase inhibitors on VEGF(165)a- and VEGF(165)b-stimulated gene transcription in HEK-293 cells expressing human VEGFR2
por: Carter, Joanne J, et al.
Publicado: (2015)

Analysis of MicroRNA Profile Alterations in Extracellular Vesicles From Mesenchymal Stromal Cells Overexpressing Stem Cell Factor
por: Zubkova, Ekaterina, et al.
Publicado: (2021)

Probing High Affinity Sequences of DNA Aptamer against VEGF(165)
por: Kaur, Harleen, et al.
Publicado: (2012)

Designing and Development of a Tandem Bivalent Nanobody against VEGF(165)
por: Khodabakhsh, Farnaz, et al.
Publicado: (2021)

Overexpression of VEGF(121), but not VEGF(165) or FGF-1, improves oxygenation in MCF-7 breast tumours
por: Fenton, B M, et al.
Publicado: (2004)

Targeting Anti-Angiogenic VEGF(165)b–VEGFR1 Signaling Promotes Nitric Oxide Independent Therapeutic Angiogenesis in Preclinical Peripheral Artery Disease Models
por: Kuppuswamy, Sivaraman, et al.
Publicado: (2022)

Development of a Multiplex Sandwich Aptamer Microarray for the Detection of VEGF(165) and Thrombin
por: Sosic, Alice, et al.
Publicado: (2013)

A pharmacokinetic binding model for bevacizumab and VEGF(165) in colorectal cancer patients
por: Panoilia, Eirini, et al.
Publicado: (2015)

Intraocular Penetration of a vNAR: In Vivo and In Vitro VEGF(165) Neutralization
por: Camacho-Villegas, Tanya A., et al.
Publicado: (2018)

The Ionophoric Activity of a Pro-Apoptotic VEGF165 Fragment on HUVEC Cells
por: Zimbone, Stefania, et al.
Publicado: (2020)

Heparin-Induced Changes of Vascular Endothelial Growth Factor (VEGF(165)) Structure
por: Nemashkalova, Ekaterina L., et al.
Publicado: (2023)

Low-potential immunosensor-based detection of the vascular growth factor 165 (VEGF(165)) using the nanocomposite platform of cobalt metal–organic framework
por: Singh, Sima, et al.
Publicado: (2020)

Transduction of rat and human adipose-tissue derived mesenchymal stromal cells by adeno-associated viral vector serotype DJ
por: Zubkova, Ekaterina S., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_i6fq7rq9hfcm53i6sth65fm072