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Ectopic Expression of Neurogenin 2 Alone is Sufficient to Induce Differentiation of Embryonic Stem Cells into Mature Neurons
Recent studies show that combinations of defined key developmental transcription factors (TFs) can reprogram somatic cells to pluripotency or induce cell conversion of one somatic cell type to another. However, it is not clear if single genes can define a cell̀s identity and if the cell fate definin...
Autores principales: | Thoma, Eva C., Wischmeyer, Erhard, Offen, Nils, Maurus, Katja, Sirén, Anna-Leena, Schartl, Manfred, Wagner, Toni U. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374837/ https://www.ncbi.nlm.nih.gov/pubmed/22719915 http://dx.doi.org/10.1371/journal.pone.0038651 |
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