Cargando…

Is There a Link between Mitochondrial Reserve Respiratory Capacity and Aging?

Oxidative phosphorylation is an indispensable resource of ATP in tissues with high requirement of energy. If the ATP demand is not met, studies suggest that this will lead to senescence and cell death in the affected tissue. The term reserve respiratory capacity or spare respiratory capacity is used...

Descripción completa

Detalles Bibliográficos
Autores principales:	Desler, Claus, Hansen, Thomas Lau, Frederiksen, Jane Bruun, Marcker, Maiken Lise, Singh, Keshav K., Juel Rasmussen, Lene
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375017/ https://www.ncbi.nlm.nih.gov/pubmed/22720157 http://dx.doi.org/10.1155/2012/192503

Ejemplares similares

The Importance of Mitochondrial DNA in Aging and Cancer
por: Desler, Claus, et al.
Publicado: (2011)

The Effect of Mitochondrial Dysfunction on Cytosolic Nucleotide Metabolism
por: Desler, Claus, et al.
Publicado: (2010)

The Role of Mitochondrial Dysfunction in the Progression of Alzheimer’s Disease
por: Desler, Claus, et al.
Publicado: (2018)

From Powerhouse to Perpetrator—Mitochondria in Health and Disease
por: Fakouri, Nima B., et al.
Publicado: (2019)

Mitochondrial Function in Gilles de la Tourette Syndrome Patients With and Without Intragenic IMMP2L Deletions
por: Bjerregaard, Victoria A., et al.
Publicado: (2020)

Mitochondrial-Linked De Novo Pyrimidine Biosynthesis Dictates Human T-Cell Proliferation but Not Expression of Effector Molecules
por: Peeters, Marlies J. W., et al.
Publicado: (2021)

In Silico screening for functional candidates amongst hypothetical proteins
por: Desler, Claus, et al.
Publicado: (2009)

Increased deoxythymidine triphosphate levels is a feature of relative cognitive decline
por: Desler, Claus, et al.
Publicado: (2015)

Bioenergetic Changes during Differentiation of Human Embryonic Stem Cells along the Hepatic Lineage
por: Hopkinson, Branden M., et al.
Publicado: (2017)

Relationships between human vitality and mitochondrial respiratory parameters, reactive oxygen species production and dNTP levels in peripheral blood mononuclear cells
por: Maynard, Scott, et al.
Publicado: (2013)

Bloom syndrome DNA helicase deficiency is associated with oxidative stress and mitochondrial network changes
por: Subramanian, Veena, et al.
Publicado: (2021)

Succinate dehydrogenase/complex II activity obligatorily links mitochondrial reserve respiratory capacity to cell survival in cardiac myocytes
por: Dhingra, R, et al.
Publicado: (2015)

Enterococcus faecalis Infection Causes Inflammation, Intracellular Oxphos-Independent ROS Production, and DNA Damage in Human Gastric Cancer Cells
por: Strickertsson, Jesper A. B., et al.
Publicado: (2013)

Simvastatin improves mitochondrial respiration in peripheral blood cells
por: Durhuus, Jon Ambæk, et al.
Publicado: (2020)

A Novel Rrm3 Function in Restricting DNA Replication via an Orc5-Binding Domain Is Genetically Separable from Rrm3 Function as an ATPase/Helicase in Facilitating Fork Progression
por: Syed, Salahuddin, et al.
Publicado: (2016)

Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease
por: Navarro, José Fernández, et al.
Publicado: (2020)

Mitochondrial complex II is a source of the reserve respiratory capacity that is regulated by metabolic sensors and promotes cell survival
por: Pfleger, J, et al.
Publicado: (2015)

Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1α axis
por: Fakouri, Nima Borhan, et al.
Publicado: (2017)

Defective mitochondrial respiration, altered dNTP pools and reduced AP endonuclease 1 activity in peripheral blood mononuclear cells of Alzheimer's disease patients
por: Maynard, Scott, et al.
Publicado: (2015)

Human DNA polymerase delta double-mutant D316A;E318A interferes with DNA mismatch repair in vitro
por: Liu, Dekang, et al.
Publicado: (2017)

14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function
por: Schoenwaelder, Simone M., et al.
Publicado: (2016)

Author Correction: Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1α axis
por: Fakouri, Nima Borhan, et al.
Publicado: (2018)

Corrigendum: 14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function
por: Schoenwaelder, Simone M., et al.
Publicado: (2017)

Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice
por: Lopez-Contreras, Andres J., et al.
Publicado: (2015)

Rev1 deficiency induces a metabolic shift in MEFs that can be manipulated by the NAD(+) precursor nicotinamide riboside
por: Anugula, Sharath, et al.
Publicado: (2023)

Enterococcus faecalis Infection and Reactive Oxygen Species Down-Regulates the miR-17-92 Cluster in Gastric Adenocarcinoma Cell Culture
por: Strickertsson, Jesper A. B., et al.
Publicado: (2014)

Socioeconomic Status, Reserve Capacity, and Depressive Symptoms Predict Pain in Rheumatoid Arthritis: An Examination of the Reserve Capacity Model
por: Azizoddin, Desiree, et al.
Publicado: (2023)

Linagliptin Regulates the Mitochondrial Respiratory Reserve to Alter Platelet Activation and Arterial Thrombosis
por: Li, Yi, et al.
Publicado: (2020)

A Link between Mitochondrial Dysregulation and Idiopathic Autism Spectrum Disorder (ASD): Alterations in Mitochondrial Respiratory Capacity and Membrane Potential
por: Hassan, Hazirah, et al.
Publicado: (2021)

Determining the functional significance of mismatch repair gene missense variants using biochemical and cellular assays
por: Heinen, Christopher D, et al.
Publicado: (2012)

Acute RyR1 Ca(2+) leak enhances NADH-linked mitochondrial respiratory capacity
por: Zanou, Nadège, et al.
Publicado: (2021)

ALDH2 Activity Reduces Mitochondrial Oxygen Reserve Capacity in Endothelial Cells and Induces Senescence Properties
por: Nannelli, G., et al.
Publicado: (2018)

Atorvastatin impairs liver mitochondrial function in obese Göttingen Minipigs but heart and skeletal muscle are not affected
por: Christiansen, Liselotte Bruun, et al.
Publicado: (2021)

Impact of Adrenomedullin on Mitochondrial Respiratory Capacity in Human Adipocyte
por: Dong, Yuanlin, et al.
Publicado: (2023)

Impact of adrenomedullin on mitochondrial respiratory capacity in human adipocyte
por: Dong, Yuanlin, et al.
Publicado: (2023)

Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells
por: Møller, Sofie H., et al.
Publicado: (2020)

Human exonuclease 1 (EXO1) activity characterization and its function on flap structures
por: Keijzers, Guido, et al.
Publicado: (2015)

Vascular flow reserve as a link between long‐term blood pressure level and physical performance capacity in mammals
por: Poulsen, Christian B., et al.
Publicado: (2016)

Physical Fitness and Mitochondrial Respiratory Capacity in Horse Skeletal Muscle
por: Votion, Dominique-Marie, et al.
Publicado: (2012)

Residual reserve index modifies the effect of amyloid pathology on fluorodeoxyglucose metabolism: Implications for efficiency and capacity in cognitive reserve
por: McKenzie, Cathryn, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_789qvuulfs6c4fbignd1irvuni