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Impact of HMGB1/TLR Ligand Complexes on HIV-1 Replication: Possible Role for Flagellin during HIV-1 Infection

Objective. We hypothesized that HMGB1 in complex with bacterial components, such as flagellin, CpG-ODN, and LPS, promotes HIV-1 replication. Furthermore, we studied the levels of antiflagellin antibodies during HIV-1-infection. Methods. Chronically HIV-1-infected U1 cells were stimulated with necrot...

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Detalles Bibliográficos
Autores principales: Nowak, Piotr, Abdurahman, Samir, Lindkvist, Annica, Troseid, Marius, Sönnerborg, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375154/
https://www.ncbi.nlm.nih.gov/pubmed/22719767
http://dx.doi.org/10.1155/2012/263836

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