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Complex Spatial Dynamics of Oncolytic Viruses In Vitro: Mathematical and Experimental Approaches
Oncolytic viruses replicate selectively in tumor cells and can serve as targeted treatment agents. While promising results have been observed in clinical trials, consistent success of therapy remains elusive. The dynamics of virus spread through tumor cell populations has been studied both experimen...
Autores principales: | Wodarz, Dominik, Hofacre, Andrew, Lau, John W., Sun, Zhiying, Fan, Hung, Komarova, Natalia L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375216/ https://www.ncbi.nlm.nih.gov/pubmed/22719239 http://dx.doi.org/10.1371/journal.pcbi.1002547 |
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