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Stimulation of Host Immune Defenses by a Small Molecule Protects C. elegans from Bacterial Infection

The nematode Caenorhabditis elegans offers currently untapped potential for carrying out high-throughput, live-animal screens of low molecular weight compound libraries to identify molecules that target a variety of cellular processes. We previously used a bacterial infection assay in C. elegans to...

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Detalles Bibliográficos
Autores principales: Pukkila-Worley, Read, Feinbaum, Rhonda, Kirienko, Natalia V., Larkins-Ford, Jonah, Conery, Annie L., Ausubel, Frederick M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375230/
https://www.ncbi.nlm.nih.gov/pubmed/22719261
http://dx.doi.org/10.1371/journal.pgen.1002733