Down-Regulation of Replication Factor C-40 (RFC40) Causes Chromosomal Missegregation in Neonatal and Hypertrophic Adult Rat Cardiac Myocytes

BACKGROUND: Adult mammalian cardiac myocytes are generally assumed to be terminally differentiated; nonetheless, a small fraction of cardiac myocytes have been shown to replicate during ventricular remodeling. However, the expression of Replication Factor C (RFC; RFC140/40/38/37/36) and DNA polymera...

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Detalles Bibliográficos
Autores principales: Ata, Hirotaka, Shrestha, Deepa, Oka, Masahiko, Ochi, Rikuo, Jong, Chian Ju, Gebb, Sarah, Benjamin, John, Schaffer, Stephen, Hobart, Holly H., Downey, James, McMurtry, Ivan, Gupte, Rakhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375256/
https://www.ncbi.nlm.nih.gov/pubmed/22720015
http://dx.doi.org/10.1371/journal.pone.0039009

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