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The YfiBNR Signal Transduction Mechanism Reveals Novel Targets for the Evolution of Persistent Pseudomonas aeruginosa in Cystic Fibrosis Airways

The genetic adaptation of pathogens in host tissue plays a key role in the establishment of chronic infections. While whole genome sequencing has opened up the analysis of genetic changes occurring during long-term infections, the identification and characterization of adaptive traits is often obscu...

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Detalles Bibliográficos
Autores principales: Malone, Jacob G., Jaeger, Tina, Manfredi, Pablo, Dötsch, Andreas, Blanka, Andrea, Bos, Raphael, Cornelis, Guy R., Häussler, Susanne, Jenal, Urs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375315/
https://www.ncbi.nlm.nih.gov/pubmed/22719254
http://dx.doi.org/10.1371/journal.ppat.1002760