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Regulation of T Cell Homeostasis and Responses by Pten
The generation of lipid products catalyzed by PI3K is critical for normal T cell homeostasis and a productive immune response. PI3K can be activated in response to antigen receptor, co-stimulatory, cytokine, and chemokine signals. Moreover, dysregulation of this pathway frequently occurs in T cell l...
Autores principales: | Newton, Ryan H., Turka, Laurence A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375464/ https://www.ncbi.nlm.nih.gov/pubmed/22715338 http://dx.doi.org/10.3389/fimmu.2012.00151 |
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