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Younger Genes Are Less Likely to Be Essential than Older Genes, and Duplicates Are Less Likely to Be Essential than Singletons of the Same Age

Recently duplicated genes are believed to often overlap in function and expression. A priori, they are thus less likely to be essential. Although this was indeed observed in yeast, mouse singletons and duplicates were reported to be equally often essential. This contradiction can only partly be expl...

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Detalles Bibliográficos
Autores principales: Chen, Wei-Hua, Trachana, Kalliopi, Lercher, Martin J., Bork, Peer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375470/
https://www.ncbi.nlm.nih.gov/pubmed/22319151
http://dx.doi.org/10.1093/molbev/mss014

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