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Gene Conversion-Like Events in the Diversification of Human Rearranged IGHV3-23*01 Gene Sequences
Gene conversion (GCV), a mechanism mediated by activation-induced cytidine deaminase (AID) is well established as a mechanism of immunoglobulin diversification in a few species. However, definitive evidence of GCV-like events in human immunoglobulin genes is scarce. The lack of evidence of GCV in hu...
Autores principales: | Duvvuri, Bhargavi, Wu, Gillian E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375636/ https://www.ncbi.nlm.nih.gov/pubmed/22715339 http://dx.doi.org/10.3389/fimmu.2012.00158 |
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