Drug-Resistant Malaria Parasites Introduced into Madagascar from Comoros Islands

To determine risk for drug-resistant malaria parasites entering Madagascar from Comoros Islands, we screened travelers. For the 141 Plasmodium falciparum isolates detected by real-time PCR, frequency of mutant alleles of genes associated with resistance to chloroquine and pyrimethamine was high. Int...

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Detalles Bibliográficos
Autores principales: Ménard, Didier, Randrianarivo-Solofoniaina, Armand Eugène, Ahmed, Bedja Said, Jahevitra, Martial, Andriantsoanirina, Landy Valérie, Rasolofomanana, Justin Ranjalahy, Rabarijaona, Léon Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2007
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375783/
https://www.ncbi.nlm.nih.gov/pubmed/18217565
http://dx.doi.org/10.3201/eid1311.070235
Descripción
Sumario:To determine risk for drug-resistant malaria parasites entering Madagascar from Comoros Islands, we screened travelers. For the 141 Plasmodium falciparum isolates detected by real-time PCR, frequency of mutant alleles of genes associated with resistance to chloroquine and pyrimethamine was high. International-level antimalarial policy and a regional antimalarial forum are needed.

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