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Reduced Anxiety and Depression-Like Behaviours in the Circadian Period Mutant Mouse Afterhours

BACKGROUND: Disruption of the circadian rhythm is a key feature of bipolar disorder. Variation in genes encoding components of the molecular circadian clock has been associated with increased risk of the disorder in clinical populations. Similarly in animal models, disruption of the circadian clock...

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Detalles Bibliográficos
Autores principales: Keers, Robert, Pedroso, Inti, Breen, Gerome, Aitchison, Kathy J., Nolan, Patrick M., Cichon, Sven, Nöthen, Markus M., Rietschel, Marcella, Schalkwyk, Leonard C., Fernandes, Cathy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376117/
https://www.ncbi.nlm.nih.gov/pubmed/22719873
http://dx.doi.org/10.1371/journal.pone.0038263