Cargando…

Development of (99m)Tc-N4-NIM for Molecular Imaging of Tumor Hypoxia

The nitro group of 2-nitroimidazole (NIM) enters the tumor cells and is bioreductively activated and fixed in the hypoxia cells. 1,4,8,11-tetraazacyclotetradecane (N4) has shown to be a stable chelator for (99m)Tc. The present study was aimed to develop (99m)Tc-cyclam-2-nitroimidazole ((99m)Tc-N4-NI...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ali, Mohammad S., Kong, Fan-Lin, Rollo, Alex, Mendez, Richard, Kohanim, Saady, Smith, Daniel Lee, Yang, David J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376529/ https://www.ncbi.nlm.nih.gov/pubmed/22719210 http://dx.doi.org/10.1155/2012/828139

Ejemplares similares

Development of Tyrosine-Based Radiotracer (99m)Tc-N4-Tyrosine for Breast Cancer Imaging
por: Kong, Fan-Lin, et al.
Publicado: (2012)

Molecular Imaging of Mesothelioma with (99m)Tc-ECG and (68)Ga-ECG
por: Zhang, Yin-Han, et al.
Publicado: (2012)

Comparison of Tc-99m maraciclatide and Tc-99m sestamibi molecular breast imaging in patients with suspected breast cancer
por: O’Connor, Michael K., et al.
Publicado: (2017)

Comparison of (99m)Tc-N-DBODC5 and (99m)Tc-MIBI of Myocardial Perfusion Imaging for Diagnosis of Coronary Artery Disease
por: Ma, Haiyan, et al.
Publicado: (2013)

Comparison of Tc-99m pertechnetate images with dual-phase Tc 99m MIBI and SPECT images in primary hyperparathyroidism
por: Sager, Sait, et al.
Publicado: (2014)

Compton imaging with (99m)Tc for human imaging
por: Sakai, Makoto, et al.
Publicado: (2019)

(99m)Tc-Radiolabeled TPGS Nanomicelles Outperform (99m)Tc-Sestamibi as Breast Cancer Imaging Agent
por: Tesan, Fiorella C., et al.
Publicado: (2019)

Comparison of [(99m)Tc]Tc-tilmanocept with [(99m)Tc]Tc-sulphur colloids and [(99m)Tc]Tc-albumin colloids for sentinel lymph node detection in patients with cutaneous malignancies of the head
por: Ooms, Mark, et al.
Publicado: (2022)

Synthesis and Evaluation of Amino Acid-Based Radiotracer (99m)Tc-N4-AMT for Breast Cancer Imaging
por: Kong, Fan-Lin, et al.
Publicado: (2011)

Imaging Hydrogen Sulfide in Hypoxic Tissue with [(99m)Tc]Tc-Gluconate
por: Kweon, Yongkyoung, et al.
Publicado: (2020)

Clinical usefulness of (99m)Tc-HYNIC-TOC, (99m)Tc(V)-DMSA, and (99m)Tc-MIBI SPECT in the evaluation of pituitary adenomas
por: Vukomanovic, Vladimir R., et al.
Publicado: (2019)

(99m)Tc-LHRH in tumor receptor imaging
por: Hao, Dawei, et al.
Publicado: (2017)

Pharmacokinetics of the phosphatidylserine tracers (99m)Tc-lactadherin and (99m)Tc-annexin V in pigs
por: Poulsen, Runa H, et al.
Publicado: (2013)

Comparative research on (99m)Tc-Rituximab and (99m)Tc-sulfur colloid in sentinel lymph node imaging of breast cancer
por: Zhang, Jing-Jie, et al.
Publicado: (2019)

Head to head comparison of [(99m)Tc]Tc(CO)(3)(NTA) and [(99m)Tc]Tc-MAG3 in patients with suspected obstruction
por: Taylor, Andrew T., et al.
Publicado: (2021)

Synthesis and Biological Evaluation of a New Nitroimidazole-(99m)Tc-Complex for Imaging of Hypoxia in Mice Model
por: Zhang, Qing, et al.
Publicado: (2016)

Synthesis and Evaluation of (99m)Tc-Labelled 2-Nitroimidazole Derivatives with Different Linkers for Tumour Hypoxia Imaging
por: Ruan, Qing, et al.
Publicado: (2023)

(99)Tc(m)-MDP Imaging of Osteopetrosis: Case Report
por: Zheng, Li-Chun, et al.
Publicado: (2015)

A novel molecular imaging probe [(99m)Tc]Tc-HYNIC-FAPI targeting cancer-associated fibroblasts
por: Jiang, Yanghongyan, et al.
Publicado: (2023)

Comparing (99m)Tc-PSMA to (99m)Tc-MDP in Prostate Cancer Staging of the Skeletal System
por: Kabunda, Joseph, et al.
Publicado: (2021)

In Vivo Imaging of Thyroid Cancer with (99m)Tc-TR1401 and (99m)Tc-TR1402: A Comparison Study in Dogs
por: Galli, Filippo, et al.
Publicado: (2021)

Nim in action
por: Picheta, Dominik
Publicado: (2017)

Sentinel lymph node detection in oral cancer: a within-patient comparison between [(99m)Tc]Tc-tilmanocept and [(99m)Tc]Tc-nanocolloid
por: den Toom, Inne J., et al.
Publicado: (2020)

(99m)Tc-besilesomab (Scintimun®) in peripheral osteomyelitis: comparison with (99m)Tc-labelled white blood cells
por: Richter, Wolf S., et al.
Publicado: (2011)

Study of Binding Kinetics and Specificity of (99m)Tc-SSS-Complex and (99m)Tc-HMPAO to Blood Cells
por: Auletta, S., et al.
Publicado: (2018)

Altered [(99m)Tc]Tc-MDP biodistribution from neutron activation sourced (99)Mo
por: Demeter, Sandor, et al.
Publicado: (2018)

Hypoxia and Exercise Increase the Transpulmonary Passage of (99m)Tc-Labeled Albumin Particles in Humans
por: Bates, Melissa L., et al.
Publicado: (2014)

Physicochemical and Biological Study of (99m)Tc and (68)Ga Radiolabelled Ciprofloxacin and Evaluation of [(99m)Tc]Tc-CIP as Potential Diagnostic Radiopharmaceutical for Diabetic Foot Syndrome Imaging
por: Koźmiński, Przemysław, et al.
Publicado: (2021)

Synthesis, Radiolabeling and Biological Evaluation of (99m)Tc-labeled Deoxyglucose Derivatives for Molecular Imaging
por: Sadeghzadeh, Masoud, et al.
Publicado: (2013)

Use of Cinacalcet and (99m)Tc-sestamibi Imaging During Pregnancy
por: Rubin, Mishaela R., et al.
Publicado: (2017)

(99m)Tc-Hynic-TOC imaging in the diagnostic of neuroendocrine tumors
por: Liepe, Knut, et al.
Publicado: (2018)

Anaphylactic Reaction to Tc-99m Macrosalb
por: Schreuder, Nanno, et al.
Publicado: (2019)

Radiolabeling and Biological Evaluation of Novel (99m)Tc-Nitrido and (99m)Tc-Oxo Complexes with 4-Methoxy-(L)-Phenylalanine Dithiocarbamate for Tumor Imaging
por: Yin, Guangxing, et al.
Publicado: (2022)

Bone turnover markers are correlated with total skeletal uptake of (99m)Tc-methylene diphosphonate ((99m)Tc-MDP)
por: Lenora, Janaka, et al.
Publicado: (2009)

Evaluation of interobserver variability of parenchymal phase of Tc-99m mercaptoacetyltriglycine and Tc-99m dimercaptosuccinic acid renal scintigraphy
por: Erdoğan, Zeynep, et al.
Publicado: (2014)

Comparison of [(99m)Tc]Tilmanocept and Filtered [(99m)Tc]Sulfur Colloid for Identification of SLNs in Breast Cancer Patients
por: Baker, Jennifer L., et al.
Publicado: (2014)

Comparison of the Relative Renal Function Calculated with 99mTc-Diethylenetriaminepentaacetic Acid and 99mTc-Dimercaptosuccinic Acid in Children
por: Çelik, Tanju, et al.
Publicado: (2014)

Regional Liver Disorder with Differences in the Accumulation of (99m)Tc-phytate and (99m)Tc-galactosyl Human Serum Albumin
por: Kotani, Kohei, et al.
Publicado: (2017)

(99m)TcO(4)(-)/(99m)Tc-MIBI dual-tracer scintigraphy for preoperative localization of parathyroid adenomas
por: Huang, Zhongke, et al.
Publicado: (2018)

(95g)Tc and (96g)Tc as alternatives to medical radioisotope (99m)Tc
por: Hayakawa, Takehito, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_fasg798ucdkbkmklcehen3stjf