Cargando…

Current Status of Treatment of Spinal and Bulbar Muscular Atrophy

Spinal and bulbar muscular atrophy (SBMA) is the first member identified among polyglutamine diseases characterized by slowly progressive muscle weakness and atrophy of the bulbar, facial, and limb muscles pathologically associated with motor neuron loss in the spinal cord and brainstem. Androgen re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tanaka, Fumiaki, Katsuno, Masahisa, Banno, Haruhiko, Suzuki, Keisuke, Adachi, Hiroaki, Sobue, Gen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376774/ https://www.ncbi.nlm.nih.gov/pubmed/22720173 http://dx.doi.org/10.1155/2012/369284

Ejemplares similares

Neuropathology and Therapeutic Intervention in Spinal and Bulbar Muscular Atrophy
por: Banno, Haruhiko, et al.
Publicado: (2009)

Swallowing markers in spinal and bulbar muscular atrophy
por: Banno, Haruhiko, et al.
Publicado: (2017)

Quantitative Assessment of Swallowing Dysfunction in Patients with Spinal and Bulbar Muscular Atrophy
por: Hashizume, Atsushi, et al.
Publicado: (2017)

Impaired muscle uptake of creatine in spinal and bulbar muscular atrophy
por: Hijikata, Yasuhiro, et al.
Publicado: (2016)

Long-term Effects of Androgen Deprivation in a Patient with Spinal and Bulbar Muscular Atrophy - A Case Report with 14 Years of Follow-up
por: Hijikata, Yasuhiro, et al.
Publicado: (2019)

Decreased Peak Expiratory Flow Associated with Muscle Fiber-Type Switching in Spinal and Bulbar Muscular Atrophy
por: Yamada, Shinichiro, et al.
Publicado: (2016)

Microarray Analysis of Gene Expression by Skeletal Muscle of Three Mouse Models of Kennedy Disease/Spinal Bulbar Muscular Atrophy
por: Mo, Kaiguo, et al.
Publicado: (2010)

Src inhibition attenuates polyglutamine-mediated neuromuscular degeneration in spinal and bulbar muscular atrophy
por: Iida, Madoka, et al.
Publicado: (2019)

Treatment with Creatine Monohydrate in Spinal and Bulbar Muscular Atrophy: Protocol for a Randomized, Double-Blind, Placebo-Controlled Trial
por: Hijikata, Yasuhiro, et al.
Publicado: (2018)

MiR-298 Counteracts Mutant Androgen Receptor Toxicity in Spinal and Bulbar Muscular Atrophy
por: Pourshafie, Naemeh, et al.
Publicado: (2016)

Development of a functional composite for the evaluation of spinal and bulbar muscular atrophy
por: Inagaki, Tomonori, et al.
Publicado: (2022)

Nucleic Acid-Based Therapeutic Approach for Spinal and Bulbar Muscular Atrophy and Related Neurological Disorders
por: Hirunagi, Tomoki, et al.
Publicado: (2022)

Mexiletine in spinal and bulbar muscular atrophy: a randomized controlled trial
por: Yamada, Shinichiro, et al.
Publicado: (2022)

Unveiling synapse pathology in spinal bulbar muscular atrophy by genome-wide transcriptome analysis of purified motor neurons derived from disease specific iPSCs
por: Onodera, Kazunari, et al.
Publicado: (2020)

The Combined Efficacy of a Two-Year Period of Cybernic Treatment With a Wearable Cyborg Hybrid-Assistive Limb and Leuprorelin Therapy in a Patient With Spinal and Bulbar Muscular Atrophy: A Case Report
por: Nakatsuji, Hideaki, et al.
Publicado: (2022)

Mid1 is associated with androgen-dependent axonal vulnerability of motor neurons in spinal and bulbar muscular atrophy
por: Ogura, Yosuke, et al.
Publicado: (2022)

Androgens in spinal and bulbar muscular atrophy
Publicado: (2012)

Mitochondrial abnormalities in spinal and bulbar muscular atrophy
por: Ranganathan, Srikanth, et al.
Publicado: (2009)

Clinical features of spinal and bulbar muscular atrophy
por: Rhodes, Lindsay E., et al.
Publicado: (2009)

The role of ubiquitination in spinal and bulbar muscular atrophy
por: Sengupta, Medha, et al.
Publicado: (2022)

Clinical Phenotyping and Biomarkers in Spinal and Bulbar Muscular Atrophy
por: Millere, Elina, et al.
Publicado: (2021)

Correlation of clinical and molecular features in spinal bulbar muscular atrophy
por: Fratta, Pietro, et al.
Publicado: (2014)

Patient‐identified impact of symptoms in spinal and bulbar muscular atrophy
por: Guber, Robert D., et al.
Publicado: (2017)

Nonalcoholic fatty liver disease in spinal and bulbar muscular atrophy
por: Guber, Robert D., et al.
Publicado: (2017)

J wave syndromes in patients with spinal and bulbar muscular atrophy
por: Steinmetz, Karoline, et al.
Publicado: (2022)

Exploring the Role of Posttranslational Modifications in Spinal and Bulbar Muscular Atrophy
por: Gogia, Neha, et al.
Publicado: (2022)

Head and Arm Tremor in X-linked Spinal and Bulbar Muscular Atrophy
por: Aicua, Irene, et al.
Publicado: (2014)

A randomized controlled trial of exercise in spinal and bulbar muscular atrophy
por: Shrader, Joseph A, et al.
Publicado: (2015)

Genotype-Phenotype Correlation in Chinese Patients with Spinal and Bulbar Muscular Atrophy
por: Ni, Wang, et al.
Publicado: (2015)

Muscle and not neuronal biomarkers correlate with severity in spinal and bulbar muscular atrophy
por: Lombardi, Vittoria, et al.
Publicado: (2019)

Increased mitophagy in the skeletal muscle of spinal and bulbar muscular atrophy patients
por: Borgia, Doriana, et al.
Publicado: (2017)

Expression of Human Endogenous Retrovirus-K in Spinal and Bulbar Muscular Atrophy
por: Rex, Cody, et al.
Publicado: (2019)

Bicalutamide and Trehalose Ameliorate Spinal and Bulbar Muscular Atrophy Pathology in Mice
por: Galbiati, Mariarita, et al.
Publicado: (2023)

Tremor in X-linked recessive spinal and bulbar muscular atrophy (Kennedy's disease)
por: Dias, Francisco A, et al.
Publicado: (2011)

Clearance of the mutant androgen receptor in motoneuronal models of spinal and bulbar muscular atrophy()
por: Rusmini, Paola, et al.
Publicado: (2013)

Nemo-like kinase is a novel regulator of spinal and bulbar muscular atrophy
por: Todd, Tiffany W, et al.
Publicado: (2015)

Evolution of bulbar function in spinal muscular atrophy type 1 treated with nusinersen
por: Weststrate, Harriet, et al.
Publicado: (2022)

Assessing Bulbar Function in Spinal Muscular Atrophy Using Patient-Reported Outcomes
por: Dunaway Young, Sally, et al.
Publicado: (2023)

Study protocol for the MEXiletine hydrochloride administration trial: a placebo-controlled, randomised, double-blind, multicentre, crossover study of its efficacy and safety in spinal and bulbar muscular atrophy (MEXPRESS)
por: Yamada, Shinichiro, et al.
Publicado: (2018)

Endoplasmic reticulum stress in spinal and bulbar muscular atrophy: a potential target for therapy
por: Montague, Karli, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_g1bs8ri5isnsji68cq2lttbvp3