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Loss of Household Protection from Use of Insecticide-Treated Nets against Pyrethroid-Resistant Mosquitoes, Benin

Pyrethroid resistance is becoming widespread in Anopheles gambiae mosquitoes, coinciding with expanded use of insecticide-treated nets (ITNs) throughout Africa. To investigate whether nets in use are still protective, we conducted household trials in northern and southern Benin, where An. gambiae mo...

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Detalles Bibliográficos
Autores principales: Asidi, Alex, N’Guessan, Raphael, Akogbeto, Martin, Curtis, Chris, Rowland, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376816/
https://www.ncbi.nlm.nih.gov/pubmed/22709930
http://dx.doi.org/10.3201/eid1807.120218
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author Asidi, Alex
N’Guessan, Raphael
Akogbeto, Martin
Curtis, Chris
Rowland, Mark
author_facet Asidi, Alex
N’Guessan, Raphael
Akogbeto, Martin
Curtis, Chris
Rowland, Mark
author_sort Asidi, Alex
collection PubMed
description Pyrethroid resistance is becoming widespread in Anopheles gambiae mosquitoes, coinciding with expanded use of insecticide-treated nets (ITNs) throughout Africa. To investigate whether nets in use are still protective, we conducted household trials in northern and southern Benin, where An. gambiae mosquitoes are susceptible and resistant, respectively, to pyrethroids. Rooms were fitted with window traps and monitored for mosquito biting and survival rates before and after the nets were treated with pyrethroid. Sleeping under an ITN in the location with resistant mosquitoes was no more protective than sleeping under an untreated net, regardless of its physical condition. By contrast, sleeping under an ITN in the location with susceptible mosquitoes decreased the odds of biting by 66%. ITNs provide little or no protection once the mosquitoes become resistant and the netting acquires holes. Resistance seriously threatens malaria control strategies based on ITN.
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spelling pubmed-33768162012-07-01 Loss of Household Protection from Use of Insecticide-Treated Nets against Pyrethroid-Resistant Mosquitoes, Benin Asidi, Alex N’Guessan, Raphael Akogbeto, Martin Curtis, Chris Rowland, Mark Emerg Infect Dis Research Pyrethroid resistance is becoming widespread in Anopheles gambiae mosquitoes, coinciding with expanded use of insecticide-treated nets (ITNs) throughout Africa. To investigate whether nets in use are still protective, we conducted household trials in northern and southern Benin, where An. gambiae mosquitoes are susceptible and resistant, respectively, to pyrethroids. Rooms were fitted with window traps and monitored for mosquito biting and survival rates before and after the nets were treated with pyrethroid. Sleeping under an ITN in the location with resistant mosquitoes was no more protective than sleeping under an untreated net, regardless of its physical condition. By contrast, sleeping under an ITN in the location with susceptible mosquitoes decreased the odds of biting by 66%. ITNs provide little or no protection once the mosquitoes become resistant and the netting acquires holes. Resistance seriously threatens malaria control strategies based on ITN. Centers for Disease Control and Prevention 2012-07 /pmc/articles/PMC3376816/ /pubmed/22709930 http://dx.doi.org/10.3201/eid1807.120218 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Asidi, Alex
N’Guessan, Raphael
Akogbeto, Martin
Curtis, Chris
Rowland, Mark
Loss of Household Protection from Use of Insecticide-Treated Nets against Pyrethroid-Resistant Mosquitoes, Benin
title Loss of Household Protection from Use of Insecticide-Treated Nets against Pyrethroid-Resistant Mosquitoes, Benin
title_full Loss of Household Protection from Use of Insecticide-Treated Nets against Pyrethroid-Resistant Mosquitoes, Benin
title_fullStr Loss of Household Protection from Use of Insecticide-Treated Nets against Pyrethroid-Resistant Mosquitoes, Benin
title_full_unstemmed Loss of Household Protection from Use of Insecticide-Treated Nets against Pyrethroid-Resistant Mosquitoes, Benin
title_short Loss of Household Protection from Use of Insecticide-Treated Nets against Pyrethroid-Resistant Mosquitoes, Benin
title_sort loss of household protection from use of insecticide-treated nets against pyrethroid-resistant mosquitoes, benin
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376816/
https://www.ncbi.nlm.nih.gov/pubmed/22709930
http://dx.doi.org/10.3201/eid1807.120218
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