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A polymorphism in a let-7 microRNA binding site of KRAS in women with endometriosis

Endometriosis is found in 5–15% of women of reproductive age and is more frequent in relatives of women with the disease. Activation of KRAS results in de novo endometriosis in mice, however, activating KRAS mutations have not been identified in women. We screened 150 women with endometriosis for a...

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Detalles Bibliográficos
Autores principales: Grechukhina, Olga, Petracco, Rafaella, Popkhadze, Shota, Massasa, Efi, Paranjape, Trupti, Chan, Elcie, Flores, Idhaliz, Weidhaas, Joanne B, Taylor, Hugh S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376847/
https://www.ncbi.nlm.nih.gov/pubmed/22307873
http://dx.doi.org/10.1002/emmm.201100200