Novel telomerase-increasing compound in mouse brain delays the onset of amyotrophic lateral sclerosis

Telomerase is expressed in the neonatal brain, in distinct regions of adult brain, and was shown to protect developing neurons from apoptosis. Telomerase reactivation by gene manipulation reverses neurodegeneration in aged telomerase-deficient mice. Hence, we and others hypothesized that increasing...

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Detalles Bibliográficos
Autores principales: Eitan, Erez, Tichon, Ailon, Gazit, Aviv, Gitler, Daniel, Slavin, Shimon, Priel, Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376858/
https://www.ncbi.nlm.nih.gov/pubmed/22351600
http://dx.doi.org/10.1002/emmm.201200212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376858/
https://www.ncbi.nlm.nih.gov/pubmed/22351600
http://dx.doi.org/10.1002/emmm.201200212

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