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The local immunological microenvironment in colorectal cancer as a prognostic factor for treatment decisions in the clinic: The way ahead

Analysis of the local immunological microenvironment in colorectal cancer lesions yielded prognostic markers. Harnessing these insights for clinical application however requires the use of sophisticated technology and algorithms, especially the robust and reproducible quantification of immune cells....

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Detalles Bibliográficos
Autores principales: Halama, Niels, Zoernig, Inka, Grabe, Niels, Jaeger, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376959/
https://www.ncbi.nlm.nih.gov/pubmed/22720213
http://dx.doi.org/10.4161/onci.1.1.18460
Descripción
Sumario:Analysis of the local immunological microenvironment in colorectal cancer lesions yielded prognostic markers. Harnessing these insights for clinical application however requires the use of sophisticated technology and algorithms, especially the robust and reproducible quantification of immune cells. These technologies are available and will allow individualized treatment decisions beyond the current standard.