The local immunological microenvironment in colorectal cancer as a prognostic factor for treatment decisions in the clinic: The way ahead

Analysis of the local immunological microenvironment in colorectal cancer lesions yielded prognostic markers. Harnessing these insights for clinical application however requires the use of sophisticated technology and algorithms, especially the robust and reproducible quantification of immune cells....

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Detalles Bibliográficos
Autores principales: Halama, Niels, Zoernig, Inka, Grabe, Niels, Jaeger, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Mini Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376959/
https://www.ncbi.nlm.nih.gov/pubmed/22720213
http://dx.doi.org/10.4161/onci.1.1.18460
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author Halama, Niels
Zoernig, Inka
Grabe, Niels
Jaeger, Dirk
author_facet Halama, Niels
Zoernig, Inka
Grabe, Niels
Jaeger, Dirk
author_sort Halama, Niels
collection PubMed
description Analysis of the local immunological microenvironment in colorectal cancer lesions yielded prognostic markers. Harnessing these insights for clinical application however requires the use of sophisticated technology and algorithms, especially the robust and reproducible quantification of immune cells. These technologies are available and will allow individualized treatment decisions beyond the current standard.
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spelling pubmed-33769592012-06-20 The local immunological microenvironment in colorectal cancer as a prognostic factor for treatment decisions in the clinic: The way ahead Halama, Niels Zoernig, Inka Grabe, Niels Jaeger, Dirk Oncoimmunology Mini Review Analysis of the local immunological microenvironment in colorectal cancer lesions yielded prognostic markers. Harnessing these insights for clinical application however requires the use of sophisticated technology and algorithms, especially the robust and reproducible quantification of immune cells. These technologies are available and will allow individualized treatment decisions beyond the current standard. Landes Bioscience 2012-01-01 /pmc/articles/PMC3376959/ /pubmed/22720213 http://dx.doi.org/10.4161/onci.1.1.18460 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Mini Review
Halama, Niels
Zoernig, Inka
Grabe, Niels
Jaeger, Dirk
The local immunological microenvironment in colorectal cancer as a prognostic factor for treatment decisions in the clinic: The way ahead
title The local immunological microenvironment in colorectal cancer as a prognostic factor for treatment decisions in the clinic: The way ahead
title_full The local immunological microenvironment in colorectal cancer as a prognostic factor for treatment decisions in the clinic: The way ahead
title_fullStr The local immunological microenvironment in colorectal cancer as a prognostic factor for treatment decisions in the clinic: The way ahead
title_full_unstemmed The local immunological microenvironment in colorectal cancer as a prognostic factor for treatment decisions in the clinic: The way ahead
title_short The local immunological microenvironment in colorectal cancer as a prognostic factor for treatment decisions in the clinic: The way ahead
title_sort local immunological microenvironment in colorectal cancer as a prognostic factor for treatment decisions in the clinic: the way ahead
topic Mini Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376959/
https://www.ncbi.nlm.nih.gov/pubmed/22720213
http://dx.doi.org/10.4161/onci.1.1.18460
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