Immunotherapy: Is it different for sarcomas?

The Janus-faced roles of macrophages in cancer imply both tumor-suppressive and -stimulating actions of these innate immune cells. Whereas the balance is toward tumor promotion in most epithelial cancers, we have recently shown that osteosarcoma metastasis seems to be inhibited by macrophages. Here...

Descripción completa

Detalles Bibliográficos
Autores principales: Cleton-Jansen, Anne-Marie, Buddingh, Emilie P., Lankester, Arjan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376989/
https://www.ncbi.nlm.nih.gov/pubmed/22720262
http://dx.doi.org/10.4161/onci.1.2.18345
Descripción
Sumario:The Janus-faced roles of macrophages in cancer imply both tumor-suppressive and -stimulating actions of these innate immune cells. Whereas the balance is toward tumor promotion in most epithelial cancers, we have recently shown that osteosarcoma metastasis seems to be inhibited by macrophages. Here we discuss the possible mechanism of this observation.

Ejemplares similares