What is the influence of vaccination’s routes on the regression of tumors located at mucosal sites?

Tumor-regressions following tumor-associated-antigen vaccination in animal models contrast with the limited clinical outcomes in cancer patients. Most animal studies however used subcutaneous-tumor-models and questions arise as whether these are relevant for tumors growing in mucosae; whether specif...

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Autores principales: Nardelli-Haefliger, Denise, Romero, Pedro, Jichlinski, Patrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376991/
https://www.ncbi.nlm.nih.gov/pubmed/22720257
http://dx.doi.org/10.4161/onci.1.2.18204
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author Nardelli-Haefliger, Denise
Romero, Pedro
Jichlinski, Patrice
author_facet Nardelli-Haefliger, Denise
Romero, Pedro
Jichlinski, Patrice
author_sort Nardelli-Haefliger, Denise
collection PubMed
description Tumor-regressions following tumor-associated-antigen vaccination in animal models contrast with the limited clinical outcomes in cancer patients. Most animal studies however used subcutaneous-tumor-models and questions arise as whether these are relevant for tumors growing in mucosae; whether specific mucosal-homing instructions are required; and how this may be influenced by the tumor.
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spelling pubmed-33769912012-06-20 What is the influence of vaccination’s routes on the regression of tumors located at mucosal sites? Nardelli-Haefliger, Denise Romero, Pedro Jichlinski, Patrice Oncoimmunology Author's View Tumor-regressions following tumor-associated-antigen vaccination in animal models contrast with the limited clinical outcomes in cancer patients. Most animal studies however used subcutaneous-tumor-models and questions arise as whether these are relevant for tumors growing in mucosae; whether specific mucosal-homing instructions are required; and how this may be influenced by the tumor. Landes Bioscience 2012-03-01 /pmc/articles/PMC3376991/ /pubmed/22720257 http://dx.doi.org/10.4161/onci.1.2.18204 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Nardelli-Haefliger, Denise
Romero, Pedro
Jichlinski, Patrice
What is the influence of vaccination’s routes on the regression of tumors located at mucosal sites?
title What is the influence of vaccination’s routes on the regression of tumors located at mucosal sites?
title_full What is the influence of vaccination’s routes on the regression of tumors located at mucosal sites?
title_fullStr What is the influence of vaccination’s routes on the regression of tumors located at mucosal sites?
title_full_unstemmed What is the influence of vaccination’s routes on the regression of tumors located at mucosal sites?
title_short What is the influence of vaccination’s routes on the regression of tumors located at mucosal sites?
title_sort what is the influence of vaccination’s routes on the regression of tumors located at mucosal sites?
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376991/
https://www.ncbi.nlm.nih.gov/pubmed/22720257
http://dx.doi.org/10.4161/onci.1.2.18204
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