Tumor immune escape in acute myeloid leukemia: Class II-associated invariant chain peptide expression as result of deficient antigen presentation

In this overview, we discuss the role of class II-associated invariant chain peptide (CLIP) in acute myeloid leukemia (AML), one of the few tumors expressing HLA class II. The clinical impact, function and regulation of CLIP expression on leukemic cells is addressed, indicating its potential as immu...

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Detalles Bibliográficos
Autores principales: van Luijn, Marvin M., Chamuleau, Martine E.D., Ossenkoppele, Gert J., van de Loosdrecht, Arjan A., Marieke van Ham, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376995/
https://www.ncbi.nlm.nih.gov/pubmed/22720245
http://dx.doi.org/10.4161/onci.1.2.18100

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