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Anti-leukemia activity of human gamma delta T cells
Two recently published articles from Siegers and colleagues detail both a novel human gamma delta T cell (GDTc) expansion protocol and a bioluminescent xenograft model of Ph(+) leukemia, in which GDTc adoptive therapy was tested. Additionally, B-cell chronic lymphocytic leukemia-derived cells were n...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Landes Bioscience
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376996/ https://www.ncbi.nlm.nih.gov/pubmed/22720255 http://dx.doi.org/10.4161/onci.1.2.18231 |
Sumario: | Two recently published articles from Siegers and colleagues detail both a novel human gamma delta T cell (GDTc) expansion protocol and a bioluminescent xenograft model of Ph(+) leukemia, in which GDTc adoptive therapy was tested. Additionally, B-cell chronic lymphocytic leukemia-derived cells were newly identified as targets of preferentially expanded Vdelta1 GDTc. |
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