Cargando…

Generation of allo-restricted peptide-specific T cells using RNA-pulsed dendritic cells: A three phase experimental procedure

Designer T cells expressing transgenic T cell receptors (TCR) with anti-tumor specificity offer new treatment options for cancer patients. We developed a three phase procedure to identify T cells of high avidity based on the fact that T cells recognizing peptides presented by allogeneic MHC efficien...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wilde, Susanne, Geiger, Christiane, Milosevic, Slavoljub, Mosetter, Barbara, Eichenlaub, Sabine, Schendel, Dolores J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2012
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376998/ https://www.ncbi.nlm.nih.gov/pubmed/22720234 http://dx.doi.org/10.4161/onci.1.2.18216

Ejemplares similares

Isolation of antigen-specific CD8+ T lymphocytes in vitro and in vivo
por: Wehner, Carina, et al.
Publicado: (2013)

Generation of tumor antigen-specific CD4+ and CD8+ T cells by simultaneous MHC-I and -II epitope presentation in vitro and in vivo
por: Wehner, Carina, et al.
Publicado: (2014)

A generic RNA-pulsed dendritic cell vaccine strategy for renal cell carcinoma
por: Geiger, Christiane, et al.
Publicado: (2005)

Three-day dendritic cells for vaccine development: Antigen uptake, processing and presentation
por: Bürdek, Maja, et al.
Publicado: (2010)

Induction and isolation of tumor antigen-specific CD4+ T lymphocytes using sorting signal directed MHC class-II expression
por: Ellinger, Christian, et al.
Publicado: (2013)

Codon Optimization of the Human Papillomavirus E7 Oncogene Induces a CD8(+) T Cell Response to a Cryptic Epitope Not Harbored by Wild-Type E7
por: Lorenz, Felix K. M., et al.
Publicado: (2015)

In vitro and in vivo priming of T cells using dendritic cells loaded with internal cell localization signals fused cancer testis antigens
por: Milosevic, Slavoljub
Publicado: (2013)

Effects of TLR agonists on maturation and function of 3-day dendritic cells from AML patients in complete remission
por: Beck, Barbara, et al.
Publicado: (2011)

High-quality and high-avidity T cell clones specific for tumor-associated antigens and how to find them
por: Wilde, Susanne, et al.
Publicado: (2012)

Next-generation dendritic cells for immunotherapy of acute myeloid leukemia
por: Schnorfeil, Frauke, et al.
Publicado: (2014)

Unbiased Identification of T-Cell Receptors Targeting Immunodominant Peptide–MHC Complexes for T-Cell Receptor Immunotherapy
por: Lorenz, Felix K.M., et al.
Publicado: (2017)

Molecular Characterization of Antigen-Peptide Pulsed Dendritic Cells: Immature Dendritic Cells Develop a Distinct Molecular Profile when Pulsed with Antigen Peptide
por: Yang, Amy X., et al.
Publicado: (2014)

A novel and effective method to generate human porcine-specific regulatory T cells with high expression of IL-10, TGF-β1 and IL-35
por: Li, Mingqian, et al.
Publicado: (2017)

Bone marrow-generated dendritic cells pulsed with a class I-restricted peptide are potent inducers of cytotoxic T lymphocytes
Publicado: (1995)

Pappalysin-1 T cell receptor transgenic allo-restricted T cells kill Ewing sarcoma in vitro and in vivo
por: Kirschner, Andreas, et al.
Publicado: (2017)

Limitations for TCR gene therapy by MHC-restricted fratricide and TCR-mediated hematopoietic stem cell toxicity
por: Schendel, Dolores J., et al.
Publicado: (2013)

T-Cells Expressing a Highly Potent PRAME-Specific T-Cell Receptor in Combination with a Chimeric PD1-41BB Co-Stimulatory Receptor Show a Favorable Preclinical Safety Profile and Strong Anti-Tumor Reactivity
por: Sailer, Nadja, et al.
Publicado: (2022)

Specific recognition and inhibition of Ewing tumour growth by antigen-specific allo-restricted cytotoxic T cells
por: Thiel, U, et al.
Publicado: (2011)

Specific recognition and inhibition of Ewing tumour growth by antigen-specific allo-restricted cytotoxic T cells
por: Thiel, U, et al.
Publicado: (2011)

A Mouse Model of Adoptive Immunotherapeutic Targeting of Autoimmune Arthritis Using Allo-Tolerogenic Dendritic Cells
por: Yang, Jie, et al.
Publicado: (2013)

P55. Dendritic cell vaccination for postremission therapy in AML
por: Lichtenegger, FS, et al.
Publicado: (2014)

PB2441: CD34+ CELL DOSE EFFECTS ON CLINICAL OUTCOMES OF ALLO-HEMATOPOIETIC STEM CELL TRANSPLANTATION (ALLO-HSCT)
por: Zhou, Shengnan, et al.
Publicado: (2023)

NOD/scid IL-2Rg(null )mice: a preclinical model system to evaluate human dendritic cell-based vaccine strategies in vivo
por: Spranger, Stefani, et al.
Publicado: (2012)

Combining chemotherapy and autologous peptide‐pulsed dendritic cells provides survival benefit in stage IV melanoma patients
por: Eisendle, Klaus, et al.
Publicado: (2020)

Allô France : méthode de français.
por: Leeman, Danielle
Publicado: (1985)

Allô France : méthode de français.
por: Leeman, Danielle
Publicado: (1987)

Allô France : méthode de français.
por: Leeman, Danielle
Publicado: (1987)

Peptide-pulsed dendritic cells induce antigen-specific CTL-mediated protective tumor immunity
Publicado: (1996)

Clinical response in Japanese metastatic melanoma patients treated with peptide cocktail-pulsed dendritic cells
por: Akiyama, Yasuto, et al.
Publicado: (2005)

Vaccination with poly(IC:LC) and peptide-pulsed autologous dendritic cells in patients with pancreatic cancer
por: Mehrotra, Shikhar, et al.
Publicado: (2017)

Magnitude of Off-Target Allo-HLA Reactivity by Third-Party Donor-Derived Virus-Specific T Cells Is Dictated by HLA-Restriction
por: Huisman, Wesley, et al.
Publicado: (2021)

Peptide-Pulsed Dendritic Cells Have Superior Ability to Induce Immune-Mediated Tissue Destruction Compared to Peptide with Adjuvant
por: Dissanayake, Dilan, et al.
Publicado: (2014)

Generation of clinical grade dendritic cells with capacity to produce biologically active IL-12p70
por: Zobywalski, Anke, et al.
Publicado: (2007)

Human HLA-A*02:01/CHM1(+) allo-restricted T cell receptor transgenic CD8(+) T Cells specifically inhibit Ewing sarcoma growth in vitro and in vivo
por: Blaeschke, Franziska, et al.
Publicado: (2016)

Genetic analysis of allogenic donor cells after successful allo-limbal epithelial transplantation in simple and cultivated limbal epithelial transplantation procedures
por: Chotikavanich, Suksri, et al.
Publicado: (2023)

Mouse nidovirus LDV infection alleviates graft versus host disease and induces type I IFN‐dependent inhibition of dendritic cells and allo‐responsive T cells
por: Gaignage, Mélanie, et al.
Publicado: (2017)

Dendritic Cells and Cryptosporidium: From Recognition to Restriction
por: Saraav, Iti, et al.
Publicado: (2023)

CD86 and IL-12p70 Are Key Players for T Helper 1 Polarization and Natural Killer Cell Activation by Toll-Like Receptor-Induced Dendritic Cells
por: Lichtenegger, Felix S., et al.
Publicado: (2012)

Allo-parapatric speciation goes offshore
por: Price, Trevor
Publicado: (2019)

Re-discovering NK cell allo-reactivity in the therapy of solid tumors
por: Castagna, Luca, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_1o6ql473mlhe3tojkp734835ks