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A novel role for granzymes in anti-tumor immunity

The cytotoxic properties of granzymes are well established, though recent publications suggest additional roles for granzymes in immunity. We demonstrated that granzymes can act as regulators of cross-presentation by dendritic cells by inducing critical “eat-me” signals on the dying tumor cell, resu...

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Detalles Bibliográficos
Autores principales: Hoves, Sabine, Sutton, Vivien R., Trapani, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377003/
https://www.ncbi.nlm.nih.gov/pubmed/22720248
http://dx.doi.org/10.4161/onci.1.2.18102