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A novel role for granzymes in anti-tumor immunity
The cytotoxic properties of granzymes are well established, though recent publications suggest additional roles for granzymes in immunity. We demonstrated that granzymes can act as regulators of cross-presentation by dendritic cells by inducing critical “eat-me” signals on the dying tumor cell, resu...
Autores principales: | Hoves, Sabine, Sutton, Vivien R., Trapani, Joseph A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377003/ https://www.ncbi.nlm.nih.gov/pubmed/22720248 http://dx.doi.org/10.4161/onci.1.2.18102 |
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