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Tumor microenvironment in NSCLC suppresses NK cells function

NK cells, which contribute to tumor immunosurveillance, are present in the microenvironment of Non-Small-Cell Lung Carcinoma. However, they display strongly altered phenotype with decreased expression of NKp30, NKp80, DNAM-1, CD16 and ILT2, and impaired cytotoxic functions. The possible mechanisms l...

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Detalles Bibliográficos
Autores principales:	Cremer, Isabelle, Fridman, Wolf Herman, Sautès-Fridman, Catherine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2012
Materias:	Author's View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377004/ https://www.ncbi.nlm.nih.gov/pubmed/22720258 http://dx.doi.org/10.4161/onci.1.2.18309

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