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Imatinib mesylate can help to direct natural immunity toward an anti-leukemic reactivity by acting on the bone marrow microenvironment

We discuss our recent findings on the increase, in chronic myeloid leukemia patients treated with imatinib, of B1 lymphocytes producing IgM anti-O-linked sugars expressed by leukemic cells, paralleled by increased B-stimulating cytokines. We propose that one important effect of imatinib treatment is...

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Detalles Bibliográficos
Autores principales: Poggi, Alessandro, Zocchi, Maria Raffaella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377005/
https://www.ncbi.nlm.nih.gov/pubmed/22720246
http://dx.doi.org/10.4161/onci.1.2.18112

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